|
|
L-methionine <=> D-methionine
|
5.1.1.10
amino-acid racemase
5.1.1.2
methionine racemase
5.1.1.21
isoleucine 2-epimerase
5.1.1.9
arginine racemase
|
–
–
–
–
|
|
|
BRENDA:
BR170
KEGG:
R00655
MetaCyc:
METHIONINE-RACEMASE-RXN
|
|
|
|
L-methionine + H+ <=> 3-methylthiopropanamine + CO2
|
4.1.1.14
valine decarboxylase
4.1.1.57
methionine decarboxylase
|
–
–
|
|
|
BRENDA:
BR317
KEGG:
R00656
MetaCyc:
METHIONINE-DECARBOXYLASE-RXN
|
|
|
|
L-methionine + H2O <=> methanethiol + 2-oxobutyrate + NH3
|
4.4.1.11
methionine gamma-lyase
|
–
|
BMK
|
|
BRENDA:
BR3437
KEGG:
R00654
MetaCyc:
METHIONINE-GAMMA-LYASE-RXN
SABIO-RK:
1038
|
|
|
|
H2O + N-formyl-L-methionine <=> L-methionine + formate
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
3.5.1.16
acetylornithine deacetylase
3.5.1.31
formylmethionine deformylase
3.5.1.87
N-carbamoyl-L-amino-acid hydrolase
3.5.1.88
peptide deformylase
|
–
–
–
–
–
|
K
|
|
BRENDA:
BR36959
KEGG:
R00653
MetaCyc:
FORMYLMETHIONINE-DEFORMYLASE-RXN
SABIO-RK:
329
|
|
|
|
elongator_tRNAMet + L-methionine + ATP <=> L-methionyl-[elongator_tRNAMet] + diphosphate + AMP
|
6.1.1.10
methionine---tRNA ligase
|
–
|
BMK
|
|
BRENDA:
BR40
KEGG:
R03659
MetaCyc:
METHIONINE--TRNA-LIGASE-RXN
SABIO-RK:
355
|
|
|
|
L-homocysteine + betaine <=> L-methionine + N,N-dimethylglycine
|
2.1.1.5
betaine---homocysteine S-methyltransferase
|
–
|
BMK
|
|
BRENDA:
BR40558
KEGG:
R02821
MetaCyc:
2.1.1.5-RXN
SABIO-RK:
2687
|
|
|
|
5-methyltetrahydropteroyl-gamma-glutamyl-gamma-glutamylglutamate + L-homocysteine <=> tetrahydropteroyl-Glu3 + L-methionine
|
2.1.1.13
methionine synthase
2.1.1.14
5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
|
–
–
|
BMK
|
|
BRENDA:
BR40568
KEGG:
R04405
MetaCyc:
HOMOCYSMET-RXN
|
|
|
|
S-methyl-L-methionine + L-homocysteine <=> H+ + L-methionine
|
2.1.1.10
homocysteine S-methyltransferase
2.1.1.14
5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
2.1.1.5
betaine---homocysteine S-methyltransferase
|
–
–
–
|
M
|
|
BRENDA:
BR40572
KEGG:
R11063
MetaCyc:
MMUM-RXN
SABIO-RK:
13306
|
|
|
|
S-adenosyl-L-methionine + L-methionine <=> S-adenosyl-L-homocysteine + S-methyl-L-methionine
|
2.1.1.12
methionine S-methyltransferase
|
–
|
M
|
|
BRENDA:
BR43875
KEGG:
R00649
MetaCyc:
METHIONINE-S-METHYLTRANSFERASE-RXN
SABIO-RK:
1034
|
|
|
|
L-homocysteine + dimethylsulfonioacetate <=> H+ + L-methionine + methylthioacetate
|
2.1.1.3
thetin---homocysteine S-methyltransferase
|
–
|
|
|
BRENDA:
BR43892
KEGG:
R04153
MetaCyc:
2.1.1.3-RXN
|
|
|
|
glyoxylate + L-methionine <=> glycine + 4-methylsulfanyl-2-oxobutanoate
|
2.6.1.15
glutamine---pyruvate transaminase
2.6.1.2
alanine transaminase
2.6.1.39
2-aminoadipate transaminase
2.6.1.44
alanine---glyoxylate transaminase
2.6.1.51
serine---pyruvate transaminase
2.6.1.60
aromatic-amino-acid---glyoxylate transaminase
2.6.1.64
glutamine---phenylpyruvate transaminase
2.6.1.73
methionine---glyoxylate transaminase
|
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BR47428
KEGG:
R00652
MetaCyc:
METHIONINE--GLYOXYLATE-TRANSAMINASE-RXN
SABIO-RK:
1037
|
|
|
|
S-adenosyl-L-methionine + F- <=> 5''-deoxy-5''-fluoroadenosine + L-methionine
|
2.5.1.63
adenosyl-fluoride synthase
|
–
|
M
|
|
BRENDA:
BR47455
KEGG:
R09637
MetaCyc:
2.5.1.63-RXN
SABIO-RK:
6766
|
|
|
|
O-acetyl-L-homoserine + methanethiol <=> L-methionine + acetate + H+
|
2.5.1.48
cystathionine gamma-synthase
2.5.1.49
O-acetylhomoserine aminocarboxypropyltransferase
|
–
–
|
M
|
|
BRENDA:
BR47497
KEGG:
R00651
MetaCyc:
O-ACETYLHOMOSERINE-THIOL-LYASE-RXN
|
|
|
|
ATP + L-methionine + H2O <=> S-adenosyl-L-methionine + phosphate + diphosphate
|
2.5.1.6
methionine adenosyltransferase
|
–
|
BMK
|
|
BRENDA:
BR47590
KEGG:
R00177
MetaCyc:
S-ADENMETSYN-RXN
SABIO-RK:
96
|
|
|
|
S-adenosyl-L-methionine + Coproporphyrinogen-III <=> protoporphyrinogen-IX + CO2 + L-methionine + 5''-deoxyadenosine
|
1.3.98.3
coproporphyrinogen dehydrogenase
|
–
|
BMK
|
|
BRENDA:
BR48612
KEGG:
R06895
MetaCyc:
HEMN-RXN
|
|
|
|
S-methyl-L-methionine + L-selenocysteine <=> Se-methyl-L-selenocysteine + L-methionine + H+
|
2.1.1
2.1.1.280
selenocysteine Se-methyltransferase
|
–
–
|
B
|
|
BRENDA:
BR49053
KEGG:
R10430
MetaCyc:
RXN-14164
|
|
|
|
S-adenosyl-L-methionine + adenine2503_in_23S_rRNA + [2Fe-2S]-center <=> S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + 2-methyladenine2503_in_23S_rRNA + [2Fe-2S]-center
|
2.1.1.192
23S rRNA (adenine2503-C2)-methyltransferase
|
–
|
|
|
BRENDA:
BR49302
MetaCyc:
RXN-11586
|
|
|
|
S-adenosyl-L-methionine + Cl- <=> 5''-chloro-5''-deoxyadenosine + L-methionine
|
2.5.1.63
adenosyl-fluoride synthase
2.5.1.94
adenosyl-chloride synthase
|
–
–
|
M
|
|
BRENDA:
BR49404
KEGG:
R09639
MetaCyc:
RXN-11714
|
|
|
|
S-adenosyl-L-methionine + H2O <=> adenosine + L-methionine + H+
|
2.5.1.B21
3.13.1.8
S-adenosyl-L-methionine hydrolase (adenosine-forming)
|
–
–
|
B
|
|
BRENDA:
BR49470
KEGG:
R12098
MetaCyc:
RXN-19155
|
|
|
|
S-adenosyl-L-methionine + adenine2503_in_23S_rRNA + [2Fe-2S]-center <=> S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + 8-methyladenine2503_in_23S_rRNA + [2Fe-2S]-center
|
2.1.1.224
23S rRNA (adenine2503-C8)-methyltransferase
|
–
|
M
|
|
BRENDA:
BR49755
MetaCyc:
RXN-12465
|
|
|
|
S-adenosyl-L-methionine + 5-amino-1-(5-phospho-D-ribosyl)imidazole <=> 2-methyl-4-amino-5-hydroxymethylpyrimidine_phosphate + 5''-deoxyadenosine + L-methionine + formate + CO + H+
|
4.1.99.17
phosphomethylpyrimidine synthase
|
–
|
BMK
|
|
BRENDA:
BR49773
KEGG:
R03472
MetaCyc:
PYRIMSYN1-RXN
|
|
|
|
S-adenosyl-L-methionine + L-tyrosine + NADPH <=> 2-iminoacetate + p-Cresol + 5''-deoxyadenosine + L-methionine + NADP+ + H+
|
4.1.99.19
2-iminoacetate synthase
|
–
|
BM
|
|
BRENDA:
BR49775
MetaCyc:
RXN-11319
|
|
|
|
S-adenosyl-L-methionine + dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose + reduced_acceptor <=> dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucopyranose + NH3 + L-methionine + 5''-deoxyadenosine + acceptor + H+
|
4.3.1.30
dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase
|
–
|
BMK
|
|
BRENDA:
BR49954
KEGG:
R08583
MetaCyc:
RXN-12769
|
|
|
|
S-adenosyl-L-methionine + 2-deoxy-scyllo-inosamine <=> 3-amino-2,3-dideoxy-scyllo-inosose + 5''-deoxyadenosine + L-methionine + H+
|
1.1.99.38
2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)
|
–
|
MK
|
|
BRENDA:
BR50146
KEGG:
R08893
MetaCyc:
RXN-13221
|
|
|
|
S-adenosyl-L-methionine + N1-methylguanine37_in_tRNAPhe + pyruvate <=> 4-demethylwyosine37_in_tRNAPhe + L-methionine + 5''-deoxyadenosine + CO2 + H2O
|
4.1.3.44
tRNA 4-demethylwyosine synthase (AdoMet-dependent)
|
–
|
M
|
|
BRENDA:
BR50763
MetaCyc:
RXN-14516
|
|
|
|
S-adenosyl-L-methionine + dehypoxanthine_futalosine <=> cyclic_dehypoxanthinyl_futalosine + L-methionine + 5''-deoxyadenosine + H+
|
1.21.98.1
cyclic dehypoxanthinyl futalosine synthase
|
–
|
BMK
|
|
BRENDA:
BR50934
KEGG:
R08588
MetaCyc:
RXN-10620
|
|
|
|
S-adenosyl-L-methionine + 3-[(1-carboxyvinyl)oxy]benzoate + H2O <=> 6-amino-6-deoxyfutalosine + L-methionine + HCO3- + H+
|
2.5.1.120
aminodeoxyfutalosine synthase
|
–
|
BMK
|
|
BRENDA:
BR50963
KEGG:
R10667
MetaCyc:
RXN-15264
|
|
|
|
S-adenosyl-L-methionine + adenine37_in_tRNA + [2Fe-2S]-center <=> S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + 2-methyladenine37_in_tRNA + [2Fe-2S]-center
|
2.1.1
2.1.1.192
23S rRNA (adenine2503-C2)-methyltransferase
|
–
–
|
|
|
BRENDA:
BR51179
MetaCyc:
RXN0-7007
|
|
|
|
S-adenosyl-L-methionine + a_bacteriochlorophyllide_c + H2O <=> bacteriochlorophyllide_e + 5''-deoxyadenosine + L-methionine + H+
|
1.17.98.2
bacteriochlorophyllide c C-71-hydroxylase
|
–
|
K
|
|
BRENDA:
BR51842
KEGG:
R11710
MetaCyc:
RXN-18413
|
|
|
|
S-adenosyl-L-methionine + magnesium_protoporphyrin_monomethyl_ester + H2O <=> divinyl_protochlorophyllide_a + 5''-deoxyadenosine + L-methionine + H+
|
1.21.98.3
anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase
|
–
|
|
|
BRENDA:
BR51844
MetaCyc:
RXN-13852
|
|
|
|
S-adenosyl-L-methionine + magnesium_protoporphyrin_monomethyl_ester + H2O <=> 131-hydroxy-magnesium-protoporphyrin_IX_13-monomethyl_ester + 5''-deoxyadenosine + L-methionine + H+
|
1.21.98.3
anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase
|
–
|
MK
|
|
BRENDA:
BR51845
KEGG:
R06268
MetaCyc:
RXN-8797
|
|
|
|
S-adenosyl-L-methionine + 131-hydroxy-magnesium-protoporphyrin_IX_13-monomethyl_ester <=> 131-oxo-magnesium-protoporphyrin_IX_13-monomethyl_ester + 5''-deoxyadenosine + L-methionine + H+
|
1.21.98.3
anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase
|
–
|
MK
|
|
BRENDA:
BR51846
KEGG:
R06269
MetaCyc:
RXN-8798
|
|
|
|
S-adenosyl-L-methionine + 131-oxo-magnesium-protoporphyrin_IX_13-monomethyl_ester <=> divinyl_protochlorophyllide_a + 5''-deoxyadenosine + L-methionine + H+
|
1.21.98.3
anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase
|
–
|
MK
|
|
BRENDA:
BR51847
KEGG:
R06270
MetaCyc:
RXN-8799
|
|
|
|
S-adenosyl-L-methionine + heme + reduced_flavodoxin <=> anaerobilin + L-methionine + 5''-deoxyadenosine + S-adenosyl-L-homocysteine + Fe2+ + flavin
|
2.1.1.342
anaerobilin synthase
|
–
|
M
|
|
BRENDA:
BR52055
KEGG:
R11700
MetaCyc:
RXN-18337
|
|
|
|
S-adenosyl-L-methionine + a_[sulfatase]-L-serine <=> a_[sulfatase]-3-oxo-L-alanine + 5''-deoxyadenosine + L-methionine + H+
|
1.1.98.7
serine-type anaerobic sulfatase-maturating enzyme
|
–
|
|
|
BRENDA:
BR52091;
BS456400
KEGG:
R12569
MetaCyc:
RXN-20179
|
|
|
|
S-adenosyl-L-methionine + a_[sulfatase]-L-cysteine + H2O <=> a_[sulfatase]-3-oxo-L-alanine + 5''-deoxyadenosine + L-methionine + Sulfide + H+
|
1.8.98.7
cysteine-type anaerobic sulfatase-maturating enzyme
|
–
|
|
|
BRENDA:
BR52096
MetaCyc:
RXN-20178
|
|
|
|
S-adenosyl-L-methionine + 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + L-tyrosine <=> 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + 2-iminoacetate + 5''-deoxyadenosine + L-methionine + H+
|
2.5.1.147
5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase
|
–
|
MK
|
|
BRENDA:
BR52490
KEGG:
R12161
MetaCyc:
RXN-19229
|
|
|
|
S-adenosyl-L-methionine + 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil <=> coenzyme_F0 + 5''-deoxyadenosine + L-methionine + NH3 + H+
|
4.3.1.32
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase
|
–
|
BMK
|
|
BRENDA:
BR52491
KEGG:
R12162
MetaCyc:
RXN-19230
|
|
|
|
S-adenosyl-L-methionine + menaquinone + reduced_flavodoxin <=> an_8-methylmenaquinone + S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + flavin + H+
|
2.1.1.350
menaquinone C8-methyltransferase
|
–
|
M
|
|
BRENDA:
BR52531
KEGG:
R12238
MetaCyc:
RXN-18515
|
|
|
|
S-adenosyl-L-methionine + 2-demethylmenaquinone + reduced_flavodoxin <=> a_2-demethyl-8-methylmenaquinone + S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + flavin + H+
|
2.1.1.350
menaquinone C8-methyltransferase
|
–
|
|
|
BRENDA:
BR52532
KEGG:
R12239
MetaCyc:
RXN-18518
|
|
|
|
S-adenosyl-L-methionine + Fe-coproporphyrin_III <=> heme + CO2 + 5''-deoxyadenosine + L-methionine
|
1.3.98.6
AdoMet-dependent heme synthase
|
–
|
MK
|
|
BRENDA:
BR52577
KEGG:
R12002
MetaCyc:
RXN-15808
|
|
|
|
L-glutamine + 4-methylsulfanyl-2-oxobutanoate <=> 2-Oxoglutaramate + L-methionine
|
2.6.1.117
L-glutamine---4-(methylsulfanyl)-2-oxobutanoate aminotransferase
2.6.1.15
glutamine---pyruvate transaminase
2.6.1.64
glutamine---phenylpyruvate transaminase
|
–
–
–
|
MK
|
|
BRENDA:
BR52923
KEGG:
R12507
MetaCyc:
RXN-15650
SABIO-RK:
10353
|
|
|
|
Gly-Met + H2O <=> glycine + L-methionine
|
3.4.13.18
cytosol nonspecific dipeptidase
3.4.24.54
mucrolysin
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
–
–
|
|
|
BRENDA:
BS17165
MetaCyc:
RXN0-6974
|
|
|
|
S-adenosyl-L-methionine + L-homocysteine <=> L-methionine + S-adenosyl-L-homocysteine + H+
|
2.1.1.10
homocysteine S-methyltransferase
2.1.1.13
methionine synthase
2.1.1.14
5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
2.1.1.280
selenocysteine Se-methyltransferase
|
–
–
–
–
|
BK
|
|
BRENDA:
BS289526;
BS419713
KEGG:
R00650
MetaCyc:
HOMOCYSTEINE-S-METHYLTRANSFERASE-RXN
SABIO-RK:
1035
|
|
|
|
L-methionine + 2-oxoglutarate <=> 4-methylsulfanyl-2-oxobutanoate + L-glutamate
|
2.6.1.1
aspartate transaminase
2.6.1.2
alanine transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.5
tyrosine transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.6
leucine transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
2.6.1.73
methionine---glyoxylate transaminase
2.6.1.88
methionine transaminase
|
–
–
–
–
–
–
–
–
–
|
K
|
|
BRENDA:
BS353528
KEGG:
R07396
MetaCyc:
RXN-14147
|
|
|
|
L-tryptophan + 4-methylsulfanyl-2-oxobutanoate <=> 3-Indole-2-oxopropanoate + L-methionine
|
2.6.1
2.6.1.27
tryptophan transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.88
methionine transaminase
2.6.1.99
L-tryptophan---pyruvate aminotransferase
|
–
–
–
–
–
|
K
|
|
BRENDA:
BS353562
KEGG:
R12055
MetaCyc:
RXN-14685
|
|
|
|
L-methionine + phenylpyruvate <=> 4-methylsulfanyl-2-oxobutanoate + L-phenylalanine
|
2.6.1.14
asparagine---oxo-acid transaminase
2.6.1.15
glutamine---pyruvate transaminase
2.6.1.28
tryptophan---phenylpyruvate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.51
serine---pyruvate transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.58
phenylalanine(histidine) transaminase
2.6.1.60
aromatic-amino-acid---glyoxylate transaminase
2.6.1.64
glutamine---phenylpyruvate transaminase
2.6.1.88
methionine transaminase
|
–
–
–
–
–
–
–
–
–
–
|
BM
|
|
BRENDA:
BS353571
MetaCyc:
RXN-7708
SABIO-RK:
11201
|
|
|
|
O-succinyl-L-homoserine + methanethiol <=> L-methionine + succinate + H+
|
2.5.1.48
cystathionine gamma-synthase
|
–
|
|
|
BRENDA:
BS354329
MetaCyc:
RXN-18602
|
|
|
|
Met-Ala + H2O <=> L-methionine + L-alanine
|
3.4.11.18
methionyl aminopeptidase
3.4.13.12
Met-Xaa dipeptidase
3.4.13.18
cytosol nonspecific dipeptidase
3.4.17.6
alanine carboxypeptidase
3.4.22.40
bleomycin hydrolase
|
–
–
–
–
–
|
|
|
BRENDA:
BS37028
MetaCyc:
RXN0-6985
|
|
|
|
H2O + ATP + L-methionine <=> phosphate + ADP + L-methionine + H+
|
7.4.2.1
ABC-type polar-amino-acid transporter
7.4.2.11
ABC-type methionine transporter
|
–
–
|
|
|
BRENDA:
BS388058
MetaCyc:
RXN0-4522
|
|
|
|
L-methionine + acetyl-CoA <=> N-acetyl-L-methionine + CoA + H+
|
2.3.1.1
amino-acid N-acetyltransferase
|
–
|
|
|
BRENDA:
BS399862
MetaCyc:
RXN0-6948
|
|
|
|
L-methionine + 2-oxoglutarate + O2 <=> methionine_sulfoxide + succinate + CO2
|
1.14.11
1.14.11.45
L-isoleucine 4-hydroxylase
1.14.11.74
L-isoleucine 31-dioxygenase
|
–
–
–
|
|
|
BRENDA:
BS430327;
BS430328
MetaCyc:
RXN-13638
|
|
|
|
S-adenosyl-L-methionine + a_3-vinyl_bacteriochlorophyllide_d + H2O <=> bacteriochlorophyllide_f + 5''-deoxyadenosine + L-methionine + H+
|
1.17.98.2
bacteriochlorophyllide c C-71-hydroxylase
|
–
|
|
|
BRENDA:
BS443892
MetaCyc:
RXN-18422
|
|
|
|
S-adenosyl-L-methionine + menaquinone-6 + reduced_flavodoxin <=> 8-methylmenaquinone-6 + S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + flavin + H+
|
2.1.1.350
menaquinone C8-methyltransferase
|
–
|
|
|
BRENDA:
BS444604
MetaCyc:
RXN-18516
|
|
|
|
L-methionine + thioredoxin_disulfide + H2O <=> methionine_sulfoxide + thioredoxin
|
1.8.4.13
L-methionine (S)-S-oxide reductase
1.8.4.14
L-methionine (R)-S-oxide reductase
1.8.4.5
methionine-S-oxide reductase
|
–
–
–
|
K
|
|
BRENDA:
BR36934
KEGG:
R02025
|
|
|
|
L-homocysteine + 5-methyltetrahydrofolate <=> L-methionine + tetrahydrofolate
|
2.1.1.13
methionine synthase
2.1.1.14
5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
|
–
–
|
BMK
|
|
BRENDA:
BR40552
KEGG:
R00946
MetaCyc:
HOMOCYSMETB12-RXN
SABIO-RK:
1260
|
|
|
|
L-methionine + thioredoxin_disulfide + H2O <=> L-methionine_(R)-S-oxide + thioredoxin
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
1.8.4.12
peptide-methionine (R)-S-oxide reductase
1.8.4.14
L-methionine (R)-S-oxide reductase
1.8.4.B3
|
–
–
–
–
|
B
|
|
BRENDA:
BR48616
KEGG:
R07608
MetaCyc:
1.8.4.14-RXN
|
|
|
|
L-methionine + thioredoxin_disulfide + H2O <=> L-methionine_(S)-sulfoxide + thioredoxin
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
1.8.4.12
peptide-methionine (R)-S-oxide reductase
1.8.4.13
L-methionine (S)-S-oxide reductase
|
–
–
–
|
|
|
BRENDA:
BR48617
KEGG:
R07606
MetaCyc:
1.8.4.13-RXN
|
|
|
|
L-methionine + a_2-oxo_carboxylate <=> 4-methylsulfanyl-2-oxobutanoate + an_aliphatic_L-amino_acid
|
2.6.1.88
methionine transaminase
|
–
|
K
|
|
BRENDA:
BR49829
KEGG:
R08618
|
|
|
|
S-adenosyl-L-methionine + a_bacteriochlorophyllide_c + H2O <=> a_7-(hydroxymethyl)-bacteriochlorophyllide_c + 5''-deoxyadenosine + L-methionine
|
1.17.98.2
bacteriochlorophyllide c C-71-hydroxylase
|
–
|
|
|
BRENDA:
BR52046
KEGG:
R11484
|
|
|
|
S-adenosyl-L-methionine + a_7-(hydroxymethyl)-bacteriochlorophyllide_c + H2O <=> a_7-(dihydroxymethyl)bacteriochlorophyllide_c + 5''-deoxyadenosine + L-methionine
|
1.17.98.2
bacteriochlorophyllide c C-71-hydroxylase
|
–
|
|
|
BRENDA:
BR52047
KEGG:
R10437
|
|
|
|
L-methionine + H2O + O2 <=> 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
|
1.13.12.9
phenylalanine 2-monooxygenase
1.4.3.2
L-amino-acid oxidase
|
–
–
|
BK
|
|
BRENDA:
BS259010
KEGG:
R00648
SABIO-RK:
1033
|
|
|
|
L-tyrosine + S-adenosyl-L-methionine + reduced_acceptor <=> 2-iminoacetate + p-Cresol + 5''-deoxyadenosine + L-methionine + acceptor + 2 H+
|
4.1.99.19
2-iminoacetate synthase
|
–
|
K
|
|
BRENDA:
BS417199
KEGG:
R10246
|
|
|
|
S-adenosyl-L-methionine + hop-22(29)-ene + reduced_acceptor <=> Adenosylhopane + L-methionine + H+ + acceptor
|
not assigned
|
–
|
M
|
|
KEGG:
R11112
MetaCyc:
RXN-13528
|
|
|
|
L-methionine <=> methanethiol + 2-aminobut-2-enoate + H+
|
4.4.1.11
methionine gamma-lyase
|
–
|
M
|
|
KEGG:
R08635
MetaCyc:
RXN-14301
|
|
|
|
S-adenosyl-L-methionine + 5-amino-1-(5-phospho-D-ribosyl)imidazole + reduced_acceptor <=> 5-hydroxybenzimidazole + phosphate + NH3 + formate + 5''-deoxyadenosine + L-methionine + H+ + acceptor
|
4.1.99.23
5-hydroxybenzimidazole synthase
|
–
|
M
|
|
KEGG:
R11919
MetaCyc:
RXN-17122
|
|
|
|
S-adenosyl-L-methionine + GTP + reduced_acceptor <=> (8S)-3,8-cyclo-7,8-dihydroguanosine_5''-triphosphate + L-methionine + 5''-deoxyadenosine + acceptor + H+
|
4.1.99.22
GTP 3',8-cyclase
|
–
|
MK
|
|
KEGG:
R09394
MetaCyc:
RXN-8340
|
|
|
|
S-adenosyl-L-methionine + cytidine_5''-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + reduced_acceptor <=> 5''-deoxyadenosine + L-methionine + S-adenosyl-L-homocysteine + cytidine_5''-{[hydroxy(2-hydroxypropyl)phosphonoyl]phosphate} + acceptor + H+
|
2.1.1.308
cytidylyl-2-hydroxyethylphosphonate methyltransferase
|
–
|
MK
|
|
KEGG:
R12497
MetaCyc:
RXN-9010
|
|
|
|
S-adenosyl-L-methionine + alpha-D-ribose_1-methylphosphonate_5-phosphate + reduced_acceptor <=> 5-phospho-alpha-D-ribose_1,2-cyclic_phosphate + methane + 5''-deoxyadenosine + L-methionine + H+ + acceptor
|
4.7.1.1
alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase
|
–
|
MK
|
|
KEGG:
R10204
MetaCyc:
RXN0-6734
|
|
|
|
dethiobiotin + sulfur-(sulfur_carrier) + 2 S-adenosyl-L-methionine + 2 [2Fe-2S]-center <=> biotin + (sulfur_carrier) + 2 L-methionine + 2 5''-deoxyadenosine + 2 [2Fe-2S]-center
|
2.8.1.6
biotin synthase
|
–
|
|
|
BRENDA:
BR48103
SABIO-RK:
13730
|
|
|
|
N-acetyl-DL-methionine + H2O <=> L-methionine + acetate
|
3.4.13.5
Xaa-methyl-His dipeptidase
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
3.5.1.15
aspartoacylase
3.5.1.16
acetylornithine deacetylase
3.5.1.68
N-formylglutamate deformylase
3.5.1.87
N-carbamoyl-L-amino-acid hydrolase
|
–
–
–
–
–
–
|
|
|
BRENDA:
BS116173;
BS140320
SABIO-RK:
7681
|
|
|
|
Met-4-nitroanilide + H2O <=> L-methionine + 4-nitroaniline
|
3.3.2.6
leukotriene-A4 hydrolase
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.14
cytosol alanyl aminopeptidase
3.4.11.18
methionyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
3.4.11.20
aminopeptidase Ey
3.4.11.22
aminopeptidase I
3.4.11.24
aminopeptidase S
3.4.11.3
cystinyl aminopeptidase
3.4.11.6
aminopeptidase B
3.4.11.B3
3.4.11.B5
3.4.11.B9
3.4.21.26
prolyl oligopeptidase
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS14575
SABIO-RK:
14023
|
|
|
|
Met-Gly + H2O <=> glycine + L-methionine
|
3.4.11.1
leucyl aminopeptidase
3.4.13.12
Met-Xaa dipeptidase
3.4.13.18
cytosol nonspecific dipeptidase
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
–
–
–
|
|
|
BRENDA:
BS189810
SABIO-RK:
12760
|
|
|
|
L-methionine + H2O + NAD+ <=> 4-methylsulfanyl-2-oxobutanoate + NH3 + NADH
|
1.4.1.1
alanine dehydrogenase
1.4.1.2
glutamate dehydrogenase
1.4.1.20
phenylalanine dehydrogenase
1.4.1.5
L-amino-acid dehydrogenase
1.4.1.8
valine dehydrogenase (NADP+)
1.4.1.9
leucine dehydrogenase
|
–
–
–
–
–
–
|
|
|
BRENDA:
BS232341
SABIO-RK:
7281
|
|
|
|
L-methionine + O2 <=> 3-(methylthio)propanamide + CO2 + H2O
|
1.13.12.3
tryptophan 2-monooxygenase
|
–
|
|
|
BRENDA:
BS288835
SABIO-RK:
14754
|
|
|
|
L-valine + 4-methylsulfanyl-2-oxobutanoate <=> 2-oxoisovalerate + L-methionine
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.88
methionine transaminase
|
–
–
–
|
|
|
BRENDA:
BS353575
SABIO-RK:
12602
|
|
|
|
L-methionine + 4-methyl-2-oxopentanoate <=> 4-methylsulfanyl-2-oxobutanoate + L-leucine
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.88
methionine transaminase
|
–
–
|
|
|
BRENDA:
BS356573
SABIO-RK:
12601
|
|
|
|
Met-Gly-Met-Met + H2O <=> Gly-Met-Met + L-methionine
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361406;
BS385006
SABIO-RK:
6747
|
|
|
|
Met-Pro-p-nitroanilide + H2O <=> L-methionine + Pro-p-nitroanilide
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361411
SABIO-RK:
6748
|
|
|
|
Leu-Met + H2O <=> L-leucine + L-methionine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
3.4.11.23
PepB aminopeptidase
|
–
–
–
–
|
|
|
BRENDA:
BS364794
SABIO-RK:
8141
|
|
|
|
Met-4-methylcoumaryl-7-amide + H2O <=> L-methionine + 7-amino-4-methylcoumarin
|
3.3.2.6
leukotriene-A4 hydrolase
3.4.11.1
leucyl aminopeptidase
3.4.11.14
cytosol alanyl aminopeptidase
3.4.11.18
methionyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
3.4.11.20
aminopeptidase Ey
3.4.11.3
cystinyl aminopeptidase
|
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS364816
SABIO-RK:
12397
|
|
|
|
Met-Phe + H2O <=> L-methionine + L-phenylalanine
|
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.20
aminopeptidase Ey
3.4.11.22
aminopeptidase I
3.4.13.18
cytosol nonspecific dipeptidase
|
–
–
–
–
|
|
|
BRENDA:
BS382150
SABIO-RK:
10570
|
|
|
|
Phe-Met + H2O <=> L-phenylalanine + L-methionine
|
3.4.11.22
aminopeptidase I
3.4.13.18
cytosol nonspecific dipeptidase
|
–
–
|
|
|
BRENDA:
BS382157
SABIO-RK:
10572
|
|
|
|
L-methionine + NADPH + O2 <=> methionine_sulfoxide + NADP+ + H2O
|
1.14.13.8
flavin-containing monooxygenase
|
–
|
|
|
BRENDA:
BS386540
SABIO-RK:
11501
|
|
|
|
methionine_sulfoxide + reduced_benzyl_viologen + H2O <=> L-methionine + Oxidized_benzyl_viologen
|
1.8.4.13
L-methionine (S)-S-oxide reductase
1.8.5.3
respiratory dimethylsulfoxide reductase
1.8.5.B1
|
–
–
–
|
|
|
BRENDA:
BS414849
SABIO-RK:
14200
|
|
|
|
Met-Gly-Gly + H2O <=> L-methionine + Gly-Gly
|
3.4.11.13
clostridial aminopeptidase
3.4.11.15
aminopeptidase Y
3.4.11.18
methionyl aminopeptidase
3.4.11.4
tripeptide aminopeptidase
|
–
–
–
–
|
|
|
BRENDA:
BS64796
SABIO-RK:
11024
|
|
|
|
Aminoacyl-L-methionine + H2O <=> L-methionine
|
3.4.13.12
Met-Xaa dipeptidase
|
–
|
K
|
|
KEGG:
R00657
|
|
|
|
dethiobiotin + Sulfur_donor + 2 S-adenosyl-L-methionine + 2 e- + 2 H+ <=> biotin + 2 L-methionine + 2 5''-Deoxyadenosine
|
2.8.1.6
biotin synthase
|
–
|
K
|
|
KEGG:
R01078
|
|
|
|
S-adenosyl-L-methionine + reduced_flavodoxin + Protein_glycine <=> 5''-Deoxyadenosine + L-methionine + reduced_flavodoxin + Protein_glycin-2-yl_radical
|
1.97.1.4
[formate-C-acetyltransferase]-activating enzyme
|
–
|
|
|
KEGG:
R04710
|
|
|
|
protein_N6-(octanoyl)lysine + an_[Fe-S]_cluster_scaffold_protein_carrying_a_[4Fe-4S]2+_cluster + 2 S-adenosyl-L-methionine + 2 [2Fe-2S]-center + 8 H+ <=> enzyme_N6-(dihydrolipoyl)lysine + an_[Fe-S]_cluster_scaffold_protein + 2 Sulfide + 4 Fe2+ + 2 L-methionine + 2 5''-Deoxyadenosine + 2 [2Fe-2S]-center
|
2.8.1.8
lipoyl synthase
|
–
|
|
|
KEGG:
R07767
|
|
|
|
2-hydroxyethylphosphonate + methylcobalamin + S-adenosyl-L-methionine + H+ + e- <=> (S)-2-hydroxypropylphosphonate + Cobalamin + 5''-Deoxyadenosine + L-methionine
|
2.1.1.308
cytidylyl-2-hydroxyethylphosphonate methyltransferase
|
–
|
|
|
KEGG:
R08862
|
|
|
|
N-acetyldemethylphosphinothricin + methylcobalamin + S-adenosyl-L-methionine + H+ + e- <=> N-acetylphosphinothricin + Cobalamin + 5''-Deoxyadenosine + L-methionine
|
2.1.1.326
N-acetyldemethylphosphinothricin P-methyltransferase
|
–
|
K
|
|
KEGG:
R08873
|
|
|
|
N-acetyldemethyl_phosphinothricin_tripeptide + methylcobalamin + S-adenosyl-L-methionine + H+ + e- <=> L-N-acetylphosphinothricin_bialophos + Cobalamin + 5''-Deoxyadenosine + L-methionine
|
2.1.1.326
N-acetyldemethylphosphinothricin P-methyltransferase
|
–
|
K
|
|
KEGG:
R08875
|
|
|
|
Se-methyl-L-selenocysteine + 4-methylsulfanyl-2-oxobutanoate <=> beta-methylselenopyruvate + L-methionine
|
2.6.1
|
–
|
K
|
|
KEGG:
R09373
|
|
|
|
S-adenosyl-L-methionine + tRNA_7-aminomethyl-7-carbaguanine <=> L-methionine + adenine + epoxyqueuosine_in_tRNA
|
2.4.99.17
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
|
–
|
|
|
KEGG:
R10220
|
|
|
|
rRNA_containing_N1-methylguanine + pyruvate + S-adenosyl-L-methionine <=> 4-Demethylwyosine_in_tRNA(Phe) + L-methionine + 5''-Deoxyadenosine + CO2 + H2O
|
4.1.3.44
tRNA 4-demethylwyosine synthase (AdoMet-dependent)
|
–
|
|
|
KEGG:
R10552
|
|
|
|
tRNA_containing_6-isopentenyladenosine + Sulfur_donor + 2 S-adenosyl-L-methionine <=> 2-methylthio-N6-dimethylallyladenine_in_tRNA + S-adenosyl-L-homocysteine + L-methionine + 5''-Deoxyadenosine
|
2.8.4.3
tRNA-2-methylthio-N6-dimethylallyladenosine synthase
|
–
|
|
|
KEGG:
R10645
|
|
|
|
tRNA_containing_6-isopentenyladenosine + Sulfur_donor + S-adenosyl-L-methionine <=> 2-Thio-N6-dimethylallyladenine_in_tRNA + L-methionine + 5''-Deoxyadenosine
|
2.8.4.3
tRNA-2-methylthio-N6-dimethylallyladenosine synthase
|
–
|
|
|
KEGG:
R10646
|
|
|
|
N6-L-Threonylcarbamoyladenine_in_tRNA + Sulfur_donor + 2 S-adenosyl-L-methionine <=> 2-Methylthio-N6-L-threonylcarbamoyladenine_in_tRNA + S-adenosyl-L-homocysteine + L-methionine + 5''-Deoxyadenosine
|
2.8.4.5
tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase
|
–
|
|
|
KEGG:
R10649
|
|
|
|
N6-L-Threonylcarbamoyladenine_in_tRNA + Sulfur_donor + S-adenosyl-L-methionine <=> 2-Thio-N6-L-threonylcarbamoyladenine_in_tRNA + L-methionine + 5''-Deoxyadenosine
|
2.8.4.5
tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase
|
–
|
|
|
KEGG:
R10650
|
|
|
|
[Ribosomal_protein_S12]-L-aspartate + Sulfur_donor + 2 S-adenosyl-L-methionine <=> [Ribosomal_protein_S12]-3-methylthioaspartate + S-adenosyl-L-homocysteine + L-methionine + 5''-Deoxyadenosine
|
2.8.4.4
[ribosomal protein S12] (aspartate89-C3)-methylthiotransferase
|
–
|
|
|
KEGG:
R10652
|
|
|
|
[Ribosomal_protein_S12]-L-aspartate + Sulfur_donor + S-adenosyl-L-methionine <=> [Ribosomal_protein_S12]-3-thioaspartate + L-methionine + 5''-Deoxyadenosine
|
2.8.4.4
[ribosomal protein S12] (aspartate89-C3)-methylthiotransferase
|
–
|
|
|
KEGG:
R10653
|
|
|
|
paromamine + S-adenosyl-L-methionine + reduced_acceptor <=> 4''-Oxolividamine + L-methionine + 5''-Deoxyadenosine + acceptor + H2O
|
not assigned
|
–
|
K
|
|
KEGG:
R11274
|
|
|
|
neamine + S-adenosyl-L-methionine + reduced_acceptor <=> 4''-Oxonebramine + L-methionine + 5''-Deoxyadenosine + acceptor + H2O
|
not assigned
|
–
|
K
|
|
KEGG:
R11275
|
|
|
|
gentamicin_A + methylcobalamin + S-adenosyl-L-methionine + H+ + e- <=> gentamicin_X2 + Cobalamin + 5''-Deoxyadenosine + L-methionine
|
2.1.1
|
–
|
K
|
|
KEGG:
R11293
|
|
|
|
gentamicin_X2 + methylcobalamin + S-adenosyl-L-methionine + H+ + e- <=> geneticin + Cobalamin + 5''-Deoxyadenosine + L-methionine
|
2.1.1
|
–
|
K
|
|
KEGG:
R11294
|
|
|
|
[Lipoyl-carrier_protein_E2]-N6-octanoyl-L-lysine + an_[Fe-S]_cluster_scaffold_protein_carrying_a_[4Fe-4S]2+_cluster + 2 S-adenosyl-L-methionine + 2 [2Fe-2S]-center + 8 H+ <=> enzyme_N6-(dihydrolipoyl)lysine + an_[Fe-S]_cluster_scaffold_protein + 2 Sulfide + 4 Fe2+ + 2 L-methionine + 2 5''-Deoxyadenosine + 2 [2Fe-2S]-center
|
2.8.1.8
lipoyl synthase
|
–
|
K
|
|
KEGG:
R12423
|
|
|
|
[glycine_cleavage_system_H]-N6-octanoyl-L-lysine + an_[Fe-S]_cluster_scaffold_protein_carrying_a_[4Fe-4S]2+_cluster + 2 S-adenosyl-L-methionine + 2 [2Fe-2S]-center + 8 H+ <=> dihydrolipoylprotein + an_[Fe-S]_cluster_scaffold_protein + 2 Sulfide + 4 Fe2+ + 2 L-methionine + 2 5''-Deoxyadenosine + 2 [2Fe-2S]-center
|
2.8.1.8
lipoyl synthase
|
–
|
K
|
|
KEGG:
R12424
|
|
|
|
S-adenosyl-L-methionine + sulfurated_[sulfur_carrier] + dethiobiotin + [2Fe-2S]-center <=> unsulfurated_[sulfur_carrier] + biotin + 5''-deoxyadenosine + L-methionine + [2Fe-2S]-center
|
2.8.1.6
biotin synthase
|
–
|
|
|
MetaCyc:
2.8.1.6-RXN
|
|
|
|
peptide_with_an_N-terminal_L-methionine + H2O <=> L-methionine + peptide
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
MetaCyc:
3.4.11.18-RXN
|
|
|
|
dipeptide_with_an_N-terminal_L-methionine + H2O <=> L-methionine + proteinogenic_amino_acid
|
3.4.13.12
Met-Xaa dipeptidase
|
–
|
|
|
MetaCyc:
3.4.13.12-RXN
|
|
|
|
L-methionine + a_2-oxo_carboxylate <=> 4-methylsulfanyl-2-oxobutanoate + proteinogenic_amino_acid
|
2.6.1.88
methionine transaminase
|
–
|
M
|
|
MetaCyc:
R15-RXN
|
|
|
|
S-adenosyl-L-methionine + inactive_ribonucleoside_triphosphate_reductase + reduced_flavodoxin <=> active_ribonucleoside_triphosphate_reductase + 5''-deoxyadenosine + L-methionine + reduced_flavodoxin + H+
|
1.97.1
|
–
|
|
|
MetaCyc:
RNTRACTIV-RXN
|
|
|
|
indole-3-acetic_acid + L-methionine + ATP <=> H+ + (indol-3-yl)acetyl-L-methionine + AMP + diphosphate
|
6.3
|
–
|
|
|
MetaCyc:
RXN-10431
|
|
|
|
S-adenosyl-L-methionine + N-acetyldemethyl_phosphinothricin_tripeptide + reduced_acceptor <=> L-N-acetylphosphinothricin_bialophos + 5''-deoxyadenosine + L-methionine + S-adenosyl-L-homocysteine + H+ + acceptor
|
2.1.1.326
N-acetyldemethylphosphinothricin P-methyltransferase
|
–
|
M
|
|
MetaCyc:
RXN-10839
|
|
|
|
S-adenosyl-L-methionine + PqqA_peptide_with_an_E-X-X-X-Y_motif <=> a_PqqA_peptide_with_linked_Glu-Tyr_residues + 5''-deoxyadenosine + L-methionine + H+
|
1.21.98.4
PqqA peptide cyclase
|
–
|
M
|
|
MetaCyc:
RXN-11176
|
|
|
|
S-adenosyl-L-methionine + Bacteriohopanetetrol + methyl-cob(III)alamin <=> 2-methylbacteriohopanetetrol + 5''-deoxyadenosine + L-methionine + cob(III)alamin
|
2.1.1
|
–
|
M
|
|
MetaCyc:
RXN-13532
|
|
|
|
S-adenosyl-L-methionine + tetrahymanol + methyl-cob(III)alamin <=> 2-methyltetrahymanol + 5''-deoxyadenosine + L-methionine + cob(III)alamin
|
2.1.1
|
–
|
M
|
|
MetaCyc:
RXN-13534
|
|
|
|
S-adenosyl-L-methionine + hopan-22-ol + methyl-cob(III)alamin <=> 2-methyldiplopterol + 5''-deoxyadenosine + L-methionine + cob(III)alamin
|
2.1.1
|
–
|
M
|
|
MetaCyc:
RXN-13535
|
|
|
|
S-adenosyl-L-methionine + N6-(dimethylallyl)adenosine37_in_tRNA + sulfurated_[sulfur_carrier] + reduced_acceptor <=> N6-(3-methylbut-2-en-1-yl)-2-thioadenosine37_in_tRNA + unsulfurated_[sulfur_carrier] + 5''-deoxyadenosine + L-methionine + acceptor + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-14480
|
|
|
|
light + S-adenosyl-L-methionine + N6-L-threonylcarbamoyladenine37_in_tRNA + sulfurated_[sulfur_carrier] + reduced_acceptor <=> 2-methylsulfanyl-N6-L-threonylcarbamoyladenine37_in_tRNA + S-adenosyl-L-homocysteine + unsulfurated_[sulfur_carrier] + 5''-deoxyadenosine + L-methionine + acceptor + H+
|
2.8.4.5
tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase
|
–
|
|
|
MetaCyc:
RXN-14531
|
|
|
|
L-methionine + H+ <=> L-methionine + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-14652
|
|
|
|
S-adenosyl-L-methionine + [glycine-cleavage_complex_H_protein]_N6-octanoyl-L-lysine + sulfurated_[sulfur_carrier] + [2Fe-2S]-center <=> [glycine-cleavage_complex_H_protein]_N6-[(R)-lipoyl]-L-lysine + L-methionine + 5''-deoxyadenosine + unsulfurated_[sulfur_carrier] + [2Fe-2S]-center
|
2.8.1.8
lipoyl synthase
|
–
|
M
|
|
MetaCyc:
RXN-14950
|
|
|
|
S-adenosyl-L-methionine + [pyruvate_dehydrogenase_E2_protein]_N6-octanoyl-L-lysine + sulfurated_[sulfur_carrier] + [2Fe-2S]-center <=> [pyruvate_dehydrogenase_E2_protein]_N6-lipoyl-L-lysine + L-methionine + 5''-deoxyadenosine + unsulfurated_[sulfur_carrier] + [2Fe-2S]-center
|
2.8.1.8
lipoyl synthase
|
–
|
M
|
|
MetaCyc:
RXN-14957
|
|
|
|
S-adenosyl-L-methionine + [2-oxoglutarate-dehydrogenase_E2_protein]_N6-octanoyl-L-lysine + sulfurated_[sulfur_carrier] + [2Fe-2S]-center <=> [2-oxoglutarate_dehydrogenase_E2_protein]_N6-lipoyl-L-lysine + L-methionine + 5''-deoxyadenosine + unsulfurated_[sulfur_carrier] + [2Fe-2S]-center
|
2.8.1.8
lipoyl synthase
|
–
|
M
|
|
MetaCyc:
RXN-14959
|
|
|
|
S-adenosyl-L-methionine + 5,10-methylenetetrahydromethanopterin + 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + [4Fe-4S]+1_iron-sulfur_cluster + reduced_acceptor <=> 2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin + 5''-deoxyadenosine + L-methionine + 7,8-dihydromethanopterin + [4Fe-4S]2+ + acceptor
|
2.1.1
|
–
|
M
|
|
MetaCyc:
RXN-15732
|
|
|
|
S-adenosyl-L-methionine + 12,18-didecarboxysiroheme + H2O <=> pre-heme_d1 + 5''-deoxyadenosine + L-methionine + propionate + H+
|
1.2.98
|
–
|
M
|
|
MetaCyc:
RXN-15806
|
|
|
|
S-adenosyl-L-methionine + 12,18-didecarboxysiroheme + reduced_acceptor <=> Fe-coproporphyrin_III + 5''-deoxyadenosine + L-methionine + acetate + acceptor + H+
|
4.1.3
|
–
|
M
|
|
MetaCyc:
RXN-15809
|
|
|
|
S-adenosyl-L-methionine + 4-amino-1-(beta-D-glucuronosyl)pyrimidin-2(1H)-one + reduced_flavodoxin <=> cytosyl-alpha-L-arabinopyranose + CO2 + 5''-deoxyadenosine + L-methionine + flavin + H+
|
1.3.98
|
–
|
|
|
MetaCyc:
RXN-15942
|
|
|
|
initiator_tRNAMet + L-methionine + ATP <=> L-methionyl-[initiator_tRNAMet] + diphosphate + AMP
|
6.1.1.10
methionine---tRNA ligase
|
–
|
M
|
|
MetaCyc:
RXN-16165
|
|
|
|
S-adenosyl-L-methionine + inactive_[choline_trimethylamine-lyase] <=> activated_[choline_trimethylamine-lyase] + 5''-deoxyadenosine + L-methionine
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-16470
|
|
|
|
proto-zwittermicin_A-L-alanyl-[PKS] + L-leucine + L-methionine + O2 + NADPH <=> proto-zwittermicin_A + pyruvoyl-L-leucyl-L-methionine + NADP+ + H2O + polyketide-[acp]
|
2.3.1
|
–
|
M
|
|
MetaCyc:
RXN-16941
|
|
|
|
L-valine + L-tryptophan + L-methionine + NADPH + H+ <=> N-methyl-L-valyl-L-tryptophanol + L-homocysteine + H2O + NADP+
|
2.3.1
|
–
|
M
|
|
MetaCyc:
RXN-17004
|
|
|
|
S-adenosyl-L-methionine + NifB_protein_with_a_K-cluster + sulfurated_[sulfur_carrier] + oxidized_ferredoxin <=> NifB_protein_with_an_L-cluster + S-adenosyl-L-homocysteine + 5''-deoxyadenosine + L-methionine + unsulfurated_[sulfur_carrier] + H+ + reduced_ferredoxin_[iron-sulfur]_cluster
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-17025
|
|
|
|
S-adenosyl-L-methionine + N-acetyldemethylphosphinothricyl-L-alanyl-L-leucine + reduced_acceptor <=> N-acetylphosphinothricyl-L-alanyl-L-leucine + 5''-deoxyadenosine + L-methionine + S-adenosyl-L-homocysteine + H+ + acceptor
|
2.1.1.326
N-acetyldemethylphosphinothricin P-methyltransferase
|
–
|
M
|
|
MetaCyc:
RXN-17197
|
|
|
|
S-adenosyl-L-methionine + N-acetyldemethylphosphinothricin + reduced_acceptor <=> N-acetylphosphinothricin + 5''-deoxyadenosine + L-methionine + S-adenosyl-L-homocysteine + H+ + acceptor
|
2.1.1.326
N-acetyldemethylphosphinothricin P-methyltransferase
|
–
|
|
|
MetaCyc:
RXN-17199
|
|
|
|
S-adenosyl-L-methionine + a_bacteriochlorophyllide_c + H2O <=> 71-hydroxybacteriochlorophyllide_c + 5''-deoxyadenosine + L-methionine + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-17454
|
|
|
|
S-adenosyl-L-methionine + (31R)-8-ethyl-12-methylbacteriochlorophyllide_c + H2O <=> (31R)-8-ethyl-71-12-methylbacteriochlorophyllide_c + 5''-deoxyadenosine + L-methionine + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-17456
|
|
|
|
S-adenosyl-L-methionine + (31R)-8,12-diethylbacteriochlorophyllide_c + H2O <=> (31R)-8,12-diethyl-71-hydroxybacteriochlorophyllide_c + 5''-deoxyadenosine + L-methionine + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-17457
|
|
|
|
S-adenosyl-L-methionine + 12-ethyl-8-isobutylbacteriochlorophyllide_c + H2O <=> 12-ethyl-71-hydroxy-8-isobutylbacteriochlorophyllide_c + 5''-deoxyadenosine + L-methionine + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-17458
|
|
|
|
S-adenosyl-L-methionine + 12-ethyl-8-propylbacteriochlorophyllide_c + H2O <=> 12-ethyl-71-hydroxy-8-propylbacteriochlorophyllide_c + 5''-deoxyadenosine + L-methionine + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-17459
|
|
|
|
S-adenosyl-L-methionine + sulfurated_[sulfur_carrier] + dethiobiotin + [2Fe-2S]-center + H+ <=> unsulfurated_[sulfur_carrier] + 9-Mercaptodethiobiotin + 5''-deoxyadenosine + L-methionine + [2Fe-2S]-center
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-17472
|
|
|
|
S-adenosyl-L-methionine + 9-Mercaptodethiobiotin <=> biotin + 5''-deoxyadenosine + L-methionine + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-17473
|
|
|
|
N-terminal-L-methionyl-L-alanyl-[protein] + H2O <=> an_N-terminal-L-alanyl-[protein] + L-methionine
|
3.4.11.18
methionyl aminopeptidase
|
–
|
M
|
|
MetaCyc:
RXN-17873
|
|
|
|
N-terminal-L-methionyl-L-cysteinyl-[protein] + H2O <=> an_N-terminal-L-cysteinyl-[protein] + L-methionine
|
3.4.11.18
methionyl aminopeptidase
|
–
|
M
|
|
MetaCyc:
RXN-17874
|
|
|
|
N-terminal-L-methionyl-glycyl-[protein] + H2O <=> glycylpeptide + L-methionine
|
3.4.11.18
methionyl aminopeptidase
|
–
|
M
|
|
MetaCyc:
RXN-17875
|
|
|
|
N-terminal-L-methionyl-L-seryl-[protein] + H2O <=> an_N-terminal-L-seryl-[protein] + L-methionine
|
3.4.11.18
methionyl aminopeptidase
|
–
|
M
|
|
MetaCyc:
RXN-17876
|
|
|
|
N-terminal-L-methionyl-L-threonyl-[protein] + H2O <=> an_N-terminal-L-threonyl-[protein] + L-methionine
|
3.4.11.18
methionyl aminopeptidase
|
–
|
M
|
|
MetaCyc:
RXN-17877
|
|
|
|
N-terminal-L-methionyl-L-valyl-[protein] + H2O <=> an_N-terminal-L-valyl-[protein] + L-methionine
|
3.4.11.18
methionyl aminopeptidase
|
–
|
M
|
|
MetaCyc:
RXN-17878
|
|
|
|
S-adenosyl-L-methionine + alpha-D-ribose-1-(2-N-acetamidomethylphosphonate)_5-phosphate + reduced_acceptor <=> 5-phospho-alpha-D-ribose_1,2-cyclic_phosphate + N-Methylacetamide + 5''-deoxyadenosine + L-methionine + H+ + acceptor
|
4.7.1.1
alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase
|
–
|
M
|
|
MetaCyc:
RXN-17956
|
|
|
|
S-adenosyl-L-methionine + alpha-D-ribose-1-[N-(phosphonomethyl)glycine]_5-phosphate + reduced_acceptor <=> 5-phospho-alpha-D-ribose_1,2-cyclic_phosphate + sarcosine + 5''-deoxyadenosine + L-methionine + acceptor
|
4.7.1.1
alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase
|
–
|
M
|
|
MetaCyc:
RXN-17959
|
|
|
|
S-adenosyl-L-methionine + 71-hydroxybacteriochlorophyllide_c + H2O <=> 71,71-dihydroxybacteriochlorophyllide_c + 5''-deoxyadenosine + L-methionine + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18412
|
|
|
|
S-adenosyl-L-methionine + (31R)-8,12-diethyl-71-hydroxybacteriochlorophyllide_c + H2O <=> (31R)-8,12-diethyl-71,71-dihydroxybacteriochlorophyllide_c + 5''-deoxyadenosine + L-methionine + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-18414
|
|
|
|
S-adenosyl-L-methionine + (31R)-8,12-diethylbacteriochlorophyllide_c + H2O <=> (31R)-8,12-diethylbacteriochlorophyllide_e + 5''-deoxyadenosine + L-methionine + H+
|
1.17.98.2
bacteriochlorophyllide c C-71-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-18415
|
|
|
|
S-adenosyl-L-methionine + 12-ethyl-71-hydroxy-8-isobutylbacteriochlorophyllide_c + H2O <=> 12-ethyl-71,71-dihydroxy-8-isobutylbacteriochlorophyllide_c + 5''-deoxyadenosine + L-methionine + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-18416
|
|
|
|
S-adenosyl-L-methionine + 12-ethyl-8-isobutylbacteriochlorophyllide_c + H2O <=> 12-ethyl-8-isobutylbacteriochlorophyllide_e + 5''-deoxyadenosine + L-methionine + H+
|
1.17.98.2
bacteriochlorophyllide c C-71-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-18417
|
|
|
|
S-adenosyl-L-methionine + (31R)-8-ethyl-71-12-methylbacteriochlorophyllide_c + H2O <=> (31R)-8-ethyl-71,71-dihydroxy-12-methylbacteriochlorophyllide_c + 5''-deoxyadenosine + L-methionine + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-18418
|
|
|
|
S-adenosyl-L-methionine + (31R)-8-ethyl-12-methylbacteriochlorophyllide_c + H2O <=> (31R)-8-ethyl-12-methylbacteriochlorophyllide_e + 5''-deoxyadenosine + L-methionine + H+
|
1.17.98.2
bacteriochlorophyllide c C-71-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-18419
|
|
|
|
S-adenosyl-L-methionine + 12-ethyl-71-hydroxy-8-propylbacteriochlorophyllide_c + H2O <=> 12-ethyl-71,71-dihydroxy-8-propylbacteriochlorophyllide_c + 5''-deoxyadenosine + L-methionine + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-18420
|
|
|
|
S-adenosyl-L-methionine + 12-ethyl-8-propylbacteriochlorophyllide_c + H2O <=> 12-ethyl-8-propylbacteriochlorophyllide_e + 5''-deoxyadenosine + L-methionine + H+
|
1.17.98.2
bacteriochlorophyllide c C-71-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-18421
|
|
|
|
S-adenosyl-L-methionine + a_3-vinyl_bacteriochlorophyllide_d + H2O <=> 71-hydroxybacteriochlorophyllide_d + 5''-deoxyadenosine + L-methionine + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18423
|
|
|
|
S-adenosyl-L-methionine + 71-hydroxybacteriochlorophyllide_d + H2O <=> 71,71-dihydroxybacteriochlorophyllide_d + 5''-deoxyadenosine + L-methionine + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18424
|
|
|
|
S-adenosyl-L-methionine + vitamin_K2 + reduced_flavodoxin <=> 8-methylmenaquinone-8 + S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + flavin + H+
|
2.1.1.350
menaquinone C8-methyltransferase
|
–
|
|
|
MetaCyc:
RXN-18517
|
|
|
|
S-adenosyl-L-methionine + 2-demethylmenaquinone-8 + reduced_flavodoxin <=> 2-demethyl-8-methylmenaquinone-8 + S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + flavin + H+
|
2.1.1.350
menaquinone C8-methyltransferase
|
–
|
|
|
MetaCyc:
RXN-18519
|
|
|
|
queuine + S-adenosyl-L-methionine <=> pre-queuine_1 + 5''-deoxyadenosine + L-methionine + 2-hydroxycyclopenta-2,4-dien-1-one + H+
|
4.3.99.M4
|
–
|
M
|
|
MetaCyc:
RXN-21034
|
|
|
|
S-adenosyl-L-methionine + [methyl_coenzyme-M_reductase]-L-arginine + reduced_acceptor <=> S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + [methyl_coenzyme-M_reductase]-(5S)-C-methyl-L-arginine + acceptor + H+
|
2.1.1.hj
|
–
|
|
|
MetaCyc:
RXN-21081
|
|
|
|
C-terminal_[mycofactocin_precursor_peptide]-glycyl-L-valyl-L-tyrosine + S-adenosyl-L-methionine <=> C-terminal_[mycofactocin_precursor_peptide]-glycyl-L-valyl-decarboxylated_L-tyrosine + CO2 + 5''-deoxyadenosine + L-methionine
|
1.3.98.g
|
–
|
M
|
|
MetaCyc:
RXN-21239
|
|
|
|
C-terminal_[mycofactocin_precursor_peptide]-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + 5''-deoxyadenosine + L-methionine + H+ + acceptor <=> C-terminal_[mycofactocin_precursor_peptide]-glycyl-L-valyl-decarboxylated_L-tyrosine + S-adenosyl-L-methionine + reduced_acceptor
|
4.1.99.q
|
–
|
M
|
|
MetaCyc:
RXN-21241
|
|
|
|
methylcob(III)alamin-[methionine_synthase] + L-homocysteine <=> cob(I)alamin-[methionine_synthase] + L-methionine + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-21538
|
|
|
|
S-adenosyl-L-methionine + 7-aminomethyl-7-deazaguanosine34_in_tRNA <=> epoxyqueuosine34_in_tRNA + adenine + L-methionine + H+
|
2.4.99.17
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
|
–
|
M
|
|
MetaCyc:
RXN0-1342
|
|
|
|
S-adenosyl-L-methionine + N6-(dimethylallyl)adenosine37_in_tRNA + sulfurated_[sulfur_carrier] + reduced_acceptor <=> N6-(3-methylbut-2-en-1-yl)-2-(methylsulfanyl)adenosine37_in_tRNA + S-adenosyl-L-homocysteine + unsulfurated_[sulfur_carrier] + 5''-deoxyadenosine + L-methionine + acceptor + H+
|
2.8.4.3
tRNA-2-methylthio-N6-dimethylallyladenosine synthase
|
–
|
|
|
MetaCyc:
RXN0-5063
|
|
|
|
S-adenosyl-L-methionine + [ribosomal_protein_S12]_L-aspartate89 + sulfurated_[sulfur_carrier] + reduced_acceptor <=> [ribosomal_protein_S12]-3-methylsulfanyl-L-aspartate89 + S-adenosyl-L-homocysteine + unsulfurated_[sulfur_carrier] + L-methionine + 5''-deoxyadenosine + acceptor + H+
|
2.8.4.4
[ribosomal protein S12] (aspartate89-C3)-methylthiotransferase
|
–
|
|
|
MetaCyc:
RXN0-6366
|
|
|
|
L-methionine + H2O2 <=> methionine_sulfoxide + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN0-6721
|
|
|
|
H+ + L-methionine <=> H+ + L-methionine
|
not assigned
|
–
|
|
|
MetaCyc:
RXN0-7050
|
|
|
|
L-methionine + H2O2 <=> L-methionine_(S)-sulfoxide + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN0-7187
|
|
|
|
L-methionine + H2O2 <=> L-methionine_(R)-S-oxide + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN0-7188
|
|
|
|
S-adenosyl-L-methionine + a_[lipoyl-carrier_protein]-N6-octanoyl-L-lysine + [Fe-S]_cluster_scaffold_protein_carrying_a_[4Fe-4S]+2_cluster + H+ + reduced_ferredoxin_[iron-sulfur]_cluster <=> enzyme_N6-(dihydrolipoyl)lysine + 5''-deoxyadenosine + L-methionine + an_[Fe-S]_cluster_scaffold_protein + S2- + Fe2+ + oxidized_ferredoxin
|
2.8.1.8
lipoyl synthase
|
–
|
M
|
|
MetaCyc:
RXN0-949
|
|
|
|
S-adenosyl-L-methionine + formate_acetyltransferase-glycine + reduced_flavodoxin <=> formate_acetyltransferase-glycine + 5''-deoxyadenosine + L-methionine + reduced_flavodoxin + H+
|
1.97.1.4
[formate-C-acetyltransferase]-activating enzyme
|
–
|
|
|
MetaCyc:
TDCEACT-RXN
|
|
|
|
N-Carbamoyl-DL-Met + H2O <=> L-methionine + CO2 + NH3
|
3.5.1.87
N-carbamoyl-L-amino-acid hydrolase
|
–
|
|
|
BRENDA:
BS432869
|
|
|
|
dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose + S-adenosyl-L-methionine <=> dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucopyranose + NH3 + L-methionine + 5''-deoxyadenosine
|
4.3.1.30
dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase
|
–
|
|
|
BRENDA:
BS415632
|
|
|
|
2-deoxy-scyllo-inosamine + S-adenosyl-L-methionine <=> 3-amino-2,3-dideoxy-scyllo-inosose + CO2 + L-methionine + 5''-deoxyadenosine
|
1.3.98.3
coproporphyrinogen dehydrogenase
|
–
|
|
|
BRENDA:
BS395504
|
|
|
|
Harderoporphyrinogen + S-adenosyl-L-methionine <=> protoporphyrinogen-IX + CO2 + L-methionine + 5''-deoxyadenosine
|
1.3.98.3
coproporphyrinogen dehydrogenase
|
–
|
|
|
BRENDA:
BS414688
|
|
|
|
5-amino-1-(5-phospho-D-ribosyl)imidazole + S-adenosyl-L-methionine + reduced_acceptor <=> 5-hydroxybenzimidazole + 5''-deoxyadenosine + L-methionine + formate + NH3 + phosphate + oxidized_acceptor
|
4.1.99.23
5-hydroxybenzimidazole synthase
|
–
|
|
|
BRENDA:
BR52270
|
|
|
|
N-carbamoyl-L-methionine + H2O <=> L-methionine + CO2 + NH3
|
3.5.1.6
beta-ureidopropionase
3.5.1.87
N-carbamoyl-L-amino-acid hydrolase
|
–
–
|
|
|
BRENDA:
BS189995
|
|
|
|
N-formyl-L-methionine + H2O <=> L-methionine + CO2
|
3.5.1.87
N-carbamoyl-L-amino-acid hydrolase
|
–
|
|
|
BRENDA:
BS414953
|
|
|
|
N6-L-threonylcarbamoyladenine37_in_tRNA + sulfur-(sulfur_carrier) + 2 S-adenosyl-L-methionine <=> 2-methylthio-N6-L-threonylcarbamoyladenine37_in_tRNA + S-adenosyl-L-homocysteine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine
|
2.8.4.5
tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase
|
–
|
|
|
BRENDA:
BS424922
|
|
|
|
2 S-adenosyl-L-methionine + L-glutamyl_gamma-phosphinic_acid + reduced_acceptor <=> S-adenosyl-L-homocysteine + 5''-deoxyadenosine + L-methionine + Phosphinothricin + oxidized_acceptor
|
2.1.1.326
N-acetyldemethylphosphinothricin P-methyltransferase
|
–
|
|
|
BRENDA:
BS436727
|
|
|
|
2 S-adenosyl-L-methionine + cytidine_5''-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + reduced_acceptor <=> S-adenosyl-L-homocysteine + 5''-deoxyadenosine + L-methionine + cytidine_5''-{[hydroxy(2-hydroxypropyl)phosphonoyl]phosphate} + oxidized_acceptor
|
2.1.1.308
cytidylyl-2-hydroxyethylphosphonate methyltransferase
|
–
|
|
|
BRENDA:
BR51180
|
|
|
|
2 S-adenosyl-L-methionine + N-acetyldemethylphosphinothricin + reduced_acceptor <=> S-adenosyl-L-homocysteine + 5''-deoxyadenosine + L-methionine + N-acetylphosphinothricin + oxidized_acceptor
|
2.1.1.326
N-acetyldemethylphosphinothricin P-methyltransferase
|
–
|
|
|
BRENDA:
BR51704
|
|
|
|
N6-dimethylallyladenine37_in_tRNA + sulfur-(sulfur_carrier) + 2 S-adenosyl-L-methionine + reduced_electron_acceptor <=> 2-(methylsulfanyl)-N6-dimethylallyladenine37_in_tRNA + S-adenosyl-L-homocysteine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine + electron_acceptor
|
2.8.4.3
tRNA-2-methylthio-N6-dimethylallyladenosine synthase
|
–
|
|
|
BRENDA:
BR50975
|
|
|
|
N6-L-threonylcarbamoyladenine37_in_tRNA + sulfur-(sulfur_carrier) + 2 S-adenosyl-L-methionine + reduced_electron_acceptor <=> 2-methylsulfanyl-N6-L-threonylcarbamoyladenine37_in_tRNA + S-adenosyl-L-homocysteine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine + electron_acceptor
|
2.8.4.5
tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase
|
–
|
|
|
BRENDA:
BR50981
|
|
|
|
L-aspartate89-[ribosomal_protein_S12] + sulfur-(sulfur_carrier) + 2 S-adenosyl-L-methionine + reduced_acceptor <=> 3-methylthio-L-aspartate89-[ribosomal_protein_S12] + S-adenosyl-L-homocysteine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine + oxidized_acceptor
|
2.8.4.4
[ribosomal protein S12] (aspartate89-C3)-methylthiotransferase
|
–
|
|
|
BRENDA:
BS436495
|
|
|
|
L-aspartate89-[ribosomal_protein_S12] + sulfur-(sulfur_carrier) + 2 S-adenosyl-L-methionine + reduced_acceptor <=> 3-(methylsulfanyl)-L-aspartate89-[ribosomal_protein_S12] + S-adenosyl-L-homocysteine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine + oxidized_acceptor
|
2.8.4.4
[ribosomal protein S12] (aspartate89-C3)-methylthiotransferase
|
–
|
|
|
BRENDA:
BR50978
|
|
|
|
N6-dimethylallyladenine37_in_tRNA + sulfur-(sulfur_carrier) + 2 S-adenosyl-L-methionine <=> 2-methylthio-N6-dimethylallyladenine37_in_tRNA + S-adenosyl-L-homocysteine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine
|
2.8.4.3
tRNA-2-methylthio-N6-dimethylallyladenosine synthase
2.8.4.4
[ribosomal protein S12] (aspartate89-C3)-methylthiotransferase
|
–
–
|
|
|
BRENDA:
BS424921
|
|
|
|
Asp89-[ribosomal_protein_S12] + sulfur-(sulfur_carrier) + 2 S-adenosyl-L-methionine <=> 3-methylthioaspartate89-[ribosomal_protein_S12] + S-adenosyl-L-homocysteine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine
|
2.8.4.4
[ribosomal protein S12] (aspartate89-C3)-methylthiotransferase
|
–
|
|
|
BRENDA:
BS424665
|
|
|
|
tRNA_containing_6-isopentenyladenosine + sulfur-(sulfur_carrier) + 2 S-adenosyl-L-methionine <=> 2-methylthio-N6-dimethylallyladenine_in_tRNA + S-adenosyl-L-homocysteine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine
|
2.8.4.3
tRNA-2-methylthio-N6-dimethylallyladenosine synthase
|
–
|
|
|
BRENDA:
BS428821
|
|
|
|
3-methylthioaspartate89-[ribosomal_protein_S12_20mer_peptide] + sulfur-(sulfur_carrier) + 2 S-adenosyl-L-methionine <=> 3,3-bismethylthioaspartate89-[ribosomal_protein_S12_20mer_peptide] + S-adenosyl-L-homocysteine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine
|
2.8.4.4
[ribosomal protein S12] (aspartate89-C3)-methylthiotransferase
|
–
|
|
|
BRENDA:
BS427989
|
|
|
|
Asp88-[ribosomal_protein_S12] + sulfur-(sulfur_carrier) + 2 S-adenosyl-L-methionine <=> 3-methylthioaspartate88-[ribosomal_protein_S12] + S-adenosyl-L-homocysteine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine
|
2.8.4.4
[ribosomal protein S12] (aspartate89-C3)-methylthiotransferase
|
–
|
|
|
BRENDA:
BS428174
|
|
|
|
Asp89-[ribosomal_protein_S12_20mer_peptide] + sulfur-(sulfur_carrier) + 2 S-adenosyl-L-methionine <=> 3-methylthioaspartate89-[ribosomal_protein_S12_20mer_peptide] + S-adenosyl-L-homocysteine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine
|
2.8.4.4
[ribosomal protein S12] (aspartate89-C3)-methylthiotransferase
|
–
|
|
|
BRENDA:
BS428175
|
|
|
|
2 S-adenosyl-L-methionine + 2-methyladenine2503_in_23S_rRNA <=> S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + 2,8-dimethyladenine2503_in_23S_rRNA
|
2.1.1.224
23S rRNA (adenine2503-C8)-methyltransferase
|
–
|
|
|
BRENDA:
BS416087
|
|
|
|
2 S-adenosyl-L-methionine + adenine2503_in_23S_rRNA + 2 reduced_[4Fe-4S]-ferredoxin <=> S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + 8-methyladenine2503_in_23S_rRNA + 2 oxidized_[4Fe-4S]_ferredoxin
|
2.1.1.224
23S rRNA (adenine2503-C8)-methyltransferase
|
–
|
|
|
BRENDA:
BS434510
|
|
|
|
2 S-adenosyl-L-methionine + adenine2503_in_23S_rRNA <=> S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + 8-methyladenine2503_in_23S_rRNA
|
2.1.1.224
23S rRNA (adenine2503-C8)-methyltransferase
|
–
|
|
|
BRENDA:
BS415543
|
|
|
|
2 S-adenosyl-L-methionine + adenine2503_in_23S_rRNA + 2 reduced_[4Fe-4S]-ferredoxin <=> S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + 2-methyladenine2503_in_23S_rRNA + 2 oxidized_[4Fe-4S]_ferredoxin
|
2.1.1.192
23S rRNA (adenine2503-C2)-methyltransferase
|
–
|
|
|
BRENDA:
BS434509
|
|
|
|
2 S-adenosyl-L-methionine + adenine2503_in_23S_rRNA <=> S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + 2-methyladenine2503_in_23S_rRNA
|
2.1.1.192
23S rRNA (adenine2503-C2)-methyltransferase
|
–
|
|
|
BRENDA:
BS407337
|
|
|
|
S-adenosyl-L-methionine + N-acetyldemethyl_phosphinothricin_tripeptide + reduced_acceptor <=> S-adenosyl-L-homocysteine + 5''-deoxyadenosine + L-methionine + L-N-acetylphosphinothricin_bialophos + oxidized_acceptor
|
2.1.1.326
N-acetyldemethylphosphinothricin P-methyltransferase
|
–
|
|
|
BRENDA:
BS437889
|
|
|
|
2 S-adenosyl-L-methionine + gentamicin_X2 <=> S-adenosyl-L-homocysteine + geneticin + 5''-deoxyadenosine + L-methionine
|
2.1.1.B120
|
–
|
|
|
BRENDA:
BR53135
|
|
|
|
2 S-adenosyl-L-methionine + adenine37_in_tRNAArg(ACG) + 2 [2Fe-2S]-center <=> 2 S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + 2-methyladenine37_in_tRNAArg(ACG) + 2 [2Fe-2S]-center
|
2.1.1.192
23S rRNA (adenine2503-C2)-methyltransferase
|
–
|
|
|
BRENDA:
BS454832
|
|
|
|
2 S-adenosyl-L-methionine + adenine37_in_tRNAAsp(GUC) + 2 [2Fe-2S]-center <=> 2 S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + 2-methyladenine37_in_tRNAAsp(GUC) + 2 [2Fe-2S]-center
|
2.1.1.192
23S rRNA (adenine2503-C2)-methyltransferase
|
–
|
|
|
BRENDA:
BS454833
|
|
|
|
2 S-adenosyl-L-methionine + adenine37_in_tRNAGln(CUG) + 2 [2Fe-2S]-center <=> 2 S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + 2-methyladenine37_in_tRNAGln(CUG) + 2 [2Fe-2S]-center
|
2.1.1.192
23S rRNA (adenine2503-C2)-methyltransferase
|
–
|
|
|
BRENDA:
BS454834
|
|
|
|
2 S-adenosyl-L-methionine + adenine37_in_tRNAGln(UUG) + 2 [2Fe-2S]-center <=> 2 S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + 2-methyladenine37_in_tRNAGln(UUG) + 2 [2Fe-2S]-center
|
2.1.1.192
23S rRNA (adenine2503-C2)-methyltransferase
|
–
|
|
|
BRENDA:
BS454835
|
|
|
|
2 S-adenosyl-L-methionine + adenine37_in_tRNAGlu(UUC) + 2 [2Fe-2S]-center <=> 2 S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + 2-methyladenine37_in_tRNAGlu(UUC) + 2 [2Fe-2S]-center
|
2.1.1.192
23S rRNA (adenine2503-C2)-methyltransferase
|
–
|
|
|
BRENDA:
BS454836
|
|
|
|
2 S-adenosyl-L-methionine + adenine37_in_tRNAHis(GUG) + 2 [2Fe-2S]-center <=> 2 S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + 2-methyladenine37_in_tRNAHis(GUG) + 2 [2Fe-2S]-center
|
2.1.1.192
23S rRNA (adenine2503-C2)-methyltransferase
|
–
|
|
|
BRENDA:
BS454837
|
|
|
|
S-adenosyl-L-methionine + DL-homocysteine <=> L-methionine + S-adenosyl-L-homocysteine
|
2.1.1.10
homocysteine S-methyltransferase
|
–
|
|
|
BRENDA:
BS389687
|
|
|
|
(R,S)-S-adenosylmethionine + L-homocysteine <=> L-methionine + S-adenosyl-L-homocysteine
|
2.1.1.10
homocysteine S-methyltransferase
|
–
|
|
|
BRENDA:
BS419699
|
|
|
|
GTP + L-methionine + H2O <=> S-guanosyl-L-methionine + phosphate + diphosphate
|
2.5.1.6
methionine adenosyltransferase
|
–
|
|
|
BRENDA:
BS355772
|
|
|
|
L-methionine + pyruvate + NADH <=> N2-(D-1-Carboxyethyl)-L-Met + NAD+
|
1.5.1.28
opine dehydrogenase
|
–
|
|
|
BRENDA:
BS73115
|
|
|
|
S-adenosyl-L-methionine + NADH + formate_acetyltransferase-glycine <=> 5''-deoxyadenosine + L-methionine + NAD+ + formate_acetyltransferase-glycine-2-yl-radical
|
1.97.1.4
[formate-C-acetyltransferase]-activating enzyme
|
–
|
|
|
BRENDA:
BS380274
|
|
|
|
L-methionine + H2O + NAD+ <=> 3-methylthio-2-oxobutanoate + NH3 + NADH
|
1.4.1.9
leucine dehydrogenase
|
–
|
|
|
BRENDA:
BS232380
|
|
|
|
N-acetyl-DL-methionine + H2O <=> N-Acetyl-D-Met + L-methionine + acetate
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS376732
|
|
|
|
CTP + L-methionine + H2O <=> S-cytosyl-L-methionine + phosphate + diphosphate
|
2.5.1.6
methionine adenosyltransferase
|
–
|
|
|
BRENDA:
BS355774
|
|
|
|
Met-NH2 + H2O <=> L-methionine + NH3
|
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.17
tryptophanyl aminopeptidase
3.5.1.101
L-proline amide hydrolase
3.5.1.57
tryptophanamidase
|
–
–
–
–
|
|
|
BRENDA:
BS140598
|
|
|
|
L-methionine + 2-mercaptoethanol <=> methanethiol + S-hydroxyethyl-L-homocysteine
|
4.4.1.11
methionine gamma-lyase
|
–
|
|
|
BRENDA:
BS430325
|
|
|
|
L-methionine + pyruvate + NADPH <=> N2-(D-1-Carboxyethyl)-L-Met + NADP+ + H2O
|
1.5.1.11
D-octopine dehydrogenase
|
–
|
|
|
BRENDA:
BS6364
|
|
|
|
S-adenosyl-L-methionine + NADPH + formate_acetyltransferase-glycine <=> 5''-deoxyadenosine + L-methionine + NADP+ + formate_acetyltransferase-glycine-2-yl-radical
|
1.97.1.4
[formate-C-acetyltransferase]-activating enzyme
|
–
|
|
|
BRENDA:
BS380275
|
|
|
|
L-methionine_(S)-sulfoxide + NADPH + H+ <=> L-methionine + NADP+ + H2O
|
1.8.4.13
L-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS383223
|
|
|
|
methionine_sulfoxide + NADPH <=> L-methionine + NADP+ + H2O
|
1.8.4.13
L-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS383219
|
|
|
|
UTP + L-methionine + H2O <=> S-urasyl-L-methionine + phosphate + diphosphate
|
2.5.1.6
methionine adenosyltransferase
|
–
|
|
|
BRENDA:
BS355773
|
|
|
|
Ac-FENAYTAVPSCIASRASILTGMS-NH2 + S-adenosyl-L-methionine + reduced_acceptor <=> Ac-FENAYTAVPS-3-oxo-L-Ala-IASRASILTGMS-NH2 + L-methionine + 5''-deoxyadenosine + acceptor + Sulfide
|
1.8.98.7
cysteine-type anaerobic sulfatase-maturating enzyme
|
–
|
|
|
BRENDA:
BS438991
|
|
|
|
[arylsulfatase]-L-serine + S-adenosyl-L-methionine + reduced_acceptor <=> [arylsulfatase]-3-oxo-L-alanine + L-methionine + 5''-deoxyadenosine + acceptor + H2O
|
1.1.98.7
serine-type anaerobic sulfatase-maturating enzyme
|
–
|
|
|
BRENDA:
BS440007
|
|
|
|
protein_N6-(octanoyl)lysine + an_[Fe-S]_cluster_scaffold_protein_carrying_a_[4Fe-4S]2+_cluster + 2 S-adenosyl-L-methionine + 2 [2Fe-2S]-center + 6 H+ <=> enzyme_N6-(dihydrolipoyl)lysine + an_[Fe-S]_cluster_scaffold_protein + 2 Sulfide + 4 Fe3+ + 2 L-methionine + 2 5''-deoxyadenosine + 2 [2Fe-2S]-center
|
2.8.1.8
lipoyl synthase
|
–
|
|
|
BRENDA:
BR48680
|
|
|
|
benzyloxycarbonyl-Met + H2O <=> benzyl_alcohol + CO2 + L-methionine
|
3.5.1.64
Nalpha-benzyloxycarbonylleucine hydrolase
|
–
|
|
|
BRENDA:
BS116356
|
|
|
|
cholecystokinin-8 + H2O <=> Tyrosine_O-sulfate + L-aspartate + L-methionine + glycine + L-tryptophan + Met-Asp-Phe-NH2
|
3.4.11.20
aminopeptidase Ey
|
–
|
|
|
BRENDA:
BS381655
|
|
|
|
Pro-Met + H2O <=> L-methionine + glycine
|
3.4.13.18
cytosol nonspecific dipeptidase
|
–
|
|
|
BRENDA:
BS393328
|
|
|
|
Met-Glu + H2O <=> L-methionine + L-glutamate
|
3.4.13.12
Met-Xaa dipeptidase
3.4.13.18
cytosol nonspecific dipeptidase
|
–
–
|
|
|
BRENDA:
BS94938
|
|
|
|
Nalpha-tert-butoxycarbonyl-L-Met + H2O <=> tert-butanol + CO2 + L-methionine
|
3.5.1.64
Nalpha-benzyloxycarbonylleucine hydrolase
|
–
|
|
|
BRENDA:
BS116377
|
|
|
|
L-Met-7-amido-4-methylcoumarin + H2O <=> L-methionine + 7-amino-4-methylcoumarin
|
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.18
methionyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
3.4.11.22
aminopeptidase I
3.4.11.4
tripeptide aminopeptidase
3.4.11.6
aminopeptidase B
|
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS364755
|
|
|
|
Met-7-amido-4-methylcoumarin <=> L-methionine + 7-amino-4-methylcoumarin
|
3.4.11.14
cytosol alanyl aminopeptidase
3.4.11.15
aminopeptidase Y
3.4.11.18
methionyl aminopeptidase
|
–
–
–
|
|
|
BRENDA:
BS361354
|
|
|
|
DL-alpha-amino-4-methylthio_butyronitrile + H2O <=> L-methionine + NH3
|
3.5.5.1
nitrilase
|
–
|
|
|
BRENDA:
BS141165
|
|
|
|
N-formyl-DL-methionine + H2O <=> L-methionine + CO2
|
3.5.1.87
N-carbamoyl-L-amino-acid hydrolase
|
–
|
|
|
BRENDA:
BS190009
|
|
|
|
2 O-acetyl-L-homoserine + dimethyl_disulfide <=> 2 L-methionine + 2 acetate
|
2.5.1.49
O-acetylhomoserine aminocarboxypropyltransferase
|
–
|
|
|
BRENDA:
BS422322
|
|
|
|
L-methionine_methyl_ester + H2O <=> L-methionine + methanol
|
3.1.1.43
alpha-amino-acid esterase
|
–
|
|
|
BRENDA:
BS64512
|
|
|
|
CoA + L-methionine <=> Met-S-CoA
|
6.1.1.10
methionine---tRNA ligase
|
–
|
|
|
BRENDA:
BS368839
|
|
|
|
ATP + L-serine + L-methionine <=> ADP + phosphate + Ser-Met
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS400224
|
|
|
|
ATP + L-methionine + L-leucine <=> ADP + phosphate + Met-Leu
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS400221
|
|
|
|
ATP + L-methionine + L-serine <=> ADP + phosphate + Met-Ser
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408632
|
|
|
|
ATP + L-glutamate + L-methionine <=> ADP + phosphate + L-glutamyl-L-methionine
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS428281
|
|
|
|
3 ATP + 4 L-methionine <=> 3 ADP + 3 phosphate + L-methionyl-L-methionyl-L-methionyl-L-methionine
|
6.3.2.B16
|
–
|
|
|
BRENDA:
BS429700
|
|
|
|
4 ATP + 5 L-methionine <=> 4 ADP + 4 phosphate + L-methionyl-L-methionyl-L-methionyl-L-methionyl-L-methionine
|
6.3.2.B16
|
–
|
|
|
BRENDA:
BS429738
|
|
|
|
2 ATP + 2 L-valine + L-methionine <=> 2 ADP + 2 phosphate + VVM
|
6.3.2.B16
|
–
|
|
|
BRENDA:
BS429633
|
|
|
|
ATP + L-methionine + beta-Alanine <=> ADP + phosphate + beta-alanyl-L-methionine
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS428302
|
|
|
|
ATP + L-aspartate + L-methionine <=> ADP + phosphate + L-aspartyl-L-methionine
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS428273
|
|
|
|
ATP + L-methionine + L-threonine <=> ADP + phosphate + Met-Thr
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408633
|
|
|
|
ATP + L-methionine + L-valine <=> ADP + phosphate + Met-Val
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408634
|
|
|
|
ATP + L-tryptophan + L-methionine <=> ADP + phosphate + Trp-Met
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408712
|
|
|
|
ATP + L-methionine + L-methionine <=> ADP + phosphate + Met-Met
|
6.3.2.49
L-alanine---L-anticapsin ligase
6.3.2.B16
|
–
–
|
|
|
BRENDA:
BS400222
|
|
|
|
ATP + L-methionine + L-isoleucine <=> ADP + phosphate + Met-Ile
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408629
|
|
|
|
ATP + L-methionine + glycine <=> ADP + phosphate + Met-Gly
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS400218
|
|
|
|
ATP + L-methionine + L-cysteine <=> ADP + phosphate + L-methionyl-L-cysteine
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS400220
|
|
|
|
ATP + L-methionine + an_aliphatic_L-amino_acid <=> ADP + phosphate + Met-Ala
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS398779
|
|
|
|
ATP + L-methionine + L-alanine <=> ADP + phosphate + Met-Ala
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS400219
|
|
|
|
ATP + L-proline + L-methionine <=> ADP + phosphate + L-Pro-L-Met
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS428332
|
|
|
|
ATP + L-phenylalanine + L-methionine <=> ADP + phosphate + Phe-Met
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408670
|
|
|
|
2 ATP + 3 L-methionine <=> 2 ADP + 2 phosphate + L-Met-L-Met-L-Met
|
6.3.2.B16
|
–
|
|
|
BRENDA:
BS429639
|
|
|
|
2 ATP + L-valine + 2 L-methionine <=> 2 ADP + 2 phosphate + L-Met-L-Met-L-Met
|
6.3.2.B16
|
–
|
|
|
BRENDA:
BS429642
|
|
|
|
ATP + L-asparagine + L-methionine <=> ADP + phosphate + L-asparaginyl-L-methionine
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS400199
|
|
|
|
ATP + H2O + L-methionine-[methionine-binding_protein][side_1] <=> ADP + phosphate + L-methionine + [methionine-binding_protein][side_1]
|
7.4.2.11
ABC-type methionine transporter
|
–
|
|
|
BRENDA:
BR52762
|
|
|
|
ATP + L-threonine + L-methionine <=> ADP + phosphate + L-threonyl-L-methionine
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS400227
|
|
|
|
ATP + L-glutamine + L-methionine <=> ADP + phosphate + L-glutaminyl-L-methionine
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408534
|
|
|
|
ATP + L-arginine + L-methionine <=> ADP + phosphate + L-arginyl-L-methionine
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408454
|
|
|
|
ATP + L-histidine + L-methionine <=> ADP + phosphate + L-histidyl-L-methionine
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408558
|
|
|
|
ATP + L-tyrosine + L-methionine <=> ADP + phosphate + L-tyrosinyl-L-methionine
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408722
|
|
|
|
L-kynurenine + 4-methylsulfanyl-2-oxobutanoate <=> Kynurenic_acid + L-methionine + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353515
|
|
|
|
Met-peptide + H2O <=> L-methionine + peptide
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS370600
|
|
|
|
MDIGAYPHFMPTNLAGDPY + H2O <=> YPHFMPTNL + AYPHFMPTNL + YPHFMPTNLA + AYPHFMPTNLAG + AYPHFMPTNLAGD + DIGAYPHFMPTNLA + DIGAYPHFMPTNLAG + YPHFMPTNLAGDPY + IGAYPHFMPTNLAGD + MDIG + MDIGA + Met-Asp + L-methionine + L-tyrosine + Pro-Tyr + GDPY + DPY
|
3.4.22.63
caspase-10
|
–
|
|
|
BRENDA:
BS418829
|
|
|
|
MDIGAYPHFMPTNLAGDPY + H2O <=> AYPHFMPTNLA + AYPHFMPTNLAGD + DIGAYPHFMPTNLAG + IGAYPHFMPTNLAGD + MDIGAYPHFMPTNL + MDIGAYPHFMPTNLA + MDIGAYPHFMPTNLAGD + MDIGAYPHFMPTNLAGDP + L-methionine + MDIG + Met-Asp + L-tyrosine + Pro-Tyr + GDPY + DPY
|
3.4.22.58
caspase-5
|
–
|
|
|
BRENDA:
BS418828
|
|
|
|
Met-enkephalin + H2O <=> L-tyrosine + L-methionine
|
3.1.1.7
acetylcholinesterase
|
–
|
|
|
BRENDA:
BS83082
|
|
|
|
S-adenosyl-L-methionine + Br- <=> 5''-deoxy-5''-bromoadenosine + L-methionine
|
2.5.1.94
adenosyl-chloride synthase
|
–
|
|
|
BRENDA:
BS415247
|
|
|
|
MAEIEIY + H2O <=> L-methionine + AEIEIY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418811
|
|
|
|
MAEWEIY + H2O <=> L-methionine + AEWEIY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418812
|
|
|
|
MAGAIHY + H2O <=> L-methionine + AGAIHY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418813
|
|
|
|
MAGIEIY + H2O <=> L-methionine + AGIEIY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418814
|
|
|
|
MAHAIHY + H2O <=> L-methionine + AHAIHY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418815
|
|
|
|
MAHIEIY + H2O <=> L-methionine + AHIEIY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418816
|
|
|
|
MAPIEIY + H2O <=> L-methionine + APIEIY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418819
|
|
|
|
MARIEIY + H2O <=> L-methionine + ARIEIY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418820
|
|
|
|
MAWIEIY + H2O <=> L-methionine + AWIEIY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418823
|
|
|
|
MGEIEIY + H2O <=> L-methionine + GEIEIY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418841
|
|
|
|
Met-tRNA + H2O <=> L-methionine + tRNAMet
|
3.1.1.29
aminoacyl-tRNA hydrolase
|
–
|
|
|
BRENDA:
BS362945
|
|
|
|
MSDFIGY + H2O <=> L-methionine + SDFIGY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418845
|
|
|
|
MTEIEIY + H2O <=> L-methionine + TEIEIY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418847
|
|
|
|
MVAAAAY + H2O <=> L-methionine + VAAAAY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418848
|
|
|
|
MVEIEIY + H2O <=> L-methionine + VEIEIY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418849
|
|
|
|
MVGVKPY + H2O <=> L-methionine + VGVKPY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418850
|
|
|
|
MVHQVLY + H2O <=> L-methionine + VHQVLY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418851
|
|
|
|
MVKIEIY + H2O <=> L-methionine + VKIEIY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418852
|
|
|
|
MVLSPAY + H2O <=> L-methionine + VLSPAY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418853
|
|
|
|
MVNPTVY + H2O <=> L-methionine + VNPTVY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418854
|
|
|
|
N-isopentanoyl-L-methionine + H2O <=> pentanoate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS392798
|
|
|
|
N-pentanoyl-L-methionine + H2O <=> pentanoate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS392807
|
|
|
|
N-cyclopentanoyl-L-methionine + H2O <=> pentanoate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS392790
|
|
|
|
L-methionine + 4-methylsulfanyl-2-oxobutanoate <=> 4-methylsulfanyl-2-oxobutanoate + L-methionine
|
2.6.1.73
methionine---glyoxylate transaminase
|
–
|
|
|
BRENDA:
BS353985
|
|
|
|
MPEIEIY + H2O <=> L-methionine + PEIEIY
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418843
|
|
|
|
Met-Leu + H2O <=> L-methionine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.23
PepB aminopeptidase
3.4.13.12
Met-Xaa dipeptidase
3.4.13.18
cytosol nonspecific dipeptidase
3.4.13.19
membrane dipeptidase
|
–
–
–
–
–
|
|
|
BRENDA:
BS364789
|
|
|
|
Met-Lys-bradykinin + H2O <=> L-methionine + L-lysine + bradykinin
|
3.4.11.14
cytosol alanyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
|
–
–
|
|
|
BRENDA:
BS361363
|
|
|
|
L-Met-D-Leu + H2O <=> L-methionine + D-Leu
|
3.4.13.19
membrane dipeptidase
|
–
|
|
|
BRENDA:
BS412295
|
|
|
|
N-decanoyl-L-Met + H2O <=> Decanoate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS414945
|
|
|
|
Met-Leu-Gly + H2O <=> L-methionine + Leu-Gly
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS412434
|
|
|
|
MVKQIESK + H2O <=> L-methionine + VKQIESK
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS432152
|
|
|
|
MVNPTVFF + H2O <=> L-methionine + VNPTVFF
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS432153
|
|
|
|
MGKVKVGV + H2O <=> L-methionine + GKVKVGV
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS432131
|
|
|
|
MGNLKSVA + H2O <=> L-methionine + GNLKSVA
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS432132
|
|
|
|
Met-Gly-Met + H2O <=> L-methionine + Gly-Met
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361419
|
|
|
|
GLLVMLGL + H2O <=> GLLV + L-methionine + Leu-Gly-Leu
|
3.4.21.76
myeloblastin
|
–
|
|
|
BRENDA:
BS449966
|
|
|
|
dethiobiotin + sulfur + 2 S-adenosyl-L-methionine <=> biotin + 2 L-methionine + 2 5''-deoxyadenosine
|
2.8.1.6
biotin synthase
|
–
|
B
|
|
BRENDA:
BS398860
|
|
|
|
9-Mercaptodethiobiotin + sulfur + S-adenosyl-L-methionine <=> biotin + L-methionine + 5''-deoxyadenosine
|
2.8.1.6
biotin synthase
|
–
|
|
|
BRENDA:
BS425851
|
|
|
|
S-adenosyl-L-methionine + 7-aminomethyl-7-deazaguanine_in_tRNA(Tyr) <=> L-methionine + adenine + epoxyqueuosine-tRNATyr
|
2.4.99.17
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
|
–
|
|
|
BRENDA:
BS419563
|
|
|
|
S-adenosyl-L-methionine + 7-(aminomethyl)-7-deazaguanine-tRNATyr <=> L-methionine + adenine + epoxyqueuosine-tRNATyr
|
2.4.99.17
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
|
–
|
|
|
BRENDA:
BS421343
|
|
|
|
S-adenosyl-L-methionine + 7-aminomethyl-7-carbaguanosine_in_tRNA(Asp) <=> L-methionine + adenine + epoxyqueuosine-tRNATyr
|
2.4.99.17
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
|
–
|
|
|
BRENDA:
BS421344
|
|
|
|
S-adenosyl-L-methionine + 7-aminomethyl-7-carbaguanosine34_in_tRNA <=> L-methionine + adenine + epoxyqueuosine34_in_tRNA
|
2.4.99.17
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
|
–
|
|
|
BRENDA:
BR50190
|
|
|
|
S-adenosyl-L-methionine + 7-aminomethyl-7-deazaguanine34_in_tRNA <=> L-methionine + adenine + epoxyqueuosine34_in_tRNA
|
2.4.99.17
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
|
–
|
|
|
BRENDA:
BS421348
|
|
|
|
S-adenosyl-L-methionine + 7-aminomethyl-7-carbaguanosine_in_tRNA <=> L-methionine + adenine + epoxyqueuosine_in_tRNA
|
2.4.99.17
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
|
–
|
|
|
BRENDA:
BS421345
|
|
|
|
S-adenosyl-L-methionine + 7-aminomethyl-7-deazaguanosine_in_tRNA <=> L-methionine + adenine + epoxyqueuosine_in_tRNA
|
2.4.99.17
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
|
–
|
|
|
BRENDA:
BS421349
|
|
|
|
S-adenosyl-L-methionine + 7-aminomethyl-7-deazaguanine_in_minihelix_RNA <=> L-methionine + adenine + epoxyqueuosine_in_minihelix_RNA
|
2.4.99.17
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
|
–
|
|
|
BRENDA:
BS421347
|
|
|
|
L-Met-Pro-7-amido-4-carbamoylmethylcoumarin + H2O <=> L-methionine + Pro-7-amido-4-carbamoylmethylcoumarin
|
3.4.11.9
Xaa-Pro aminopeptidase
|
–
|
|
|
BRENDA:
BS450180
|
|
|
|
Met-Gly-Met-Phe + H2O <=> Gly-Met-Phe + L-methionine
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS450275
|
|
|
|
MTNKSSLKNN-OH + H2O <=> L-methionine + TNKSSLKNN-OH
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS450303
|
|
|
|
4-methylsulfanyl-2-oxobutanoate + L-isoleucine <=> L-methionine + 2-oxomethylvalerate
|
2.6.1.88
methionine transaminase
|
–
|
|
|
BRENDA:
BS416167
|
|
|
|
D-glutamine + L-methionine <=> D-Glu-Met + NH3
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS376623
|
|
|
|
2-oxosuccinamic_acid + L-methionine <=> L-asparagine + 4-methylsulfanyl-2-oxobutanoate
|
2.6.1.14
asparagine---oxo-acid transaminase
|
–
|
|
|
BRENDA:
BS354189
|
|
|
|
N-isobutanoyl-L-methionine + H2O <=> Isobutyrate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS392797
|
|
|
|
L-Met-PSI[C(O)S]Gly-L-Phe + H2O <=> L-methionine + Gly-Phe
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361412
|
|
|
|
5-methyltetrahydropteroylmonoglutamate + L-homocysteine <=> tetrahydrofolate + L-methionine
|
2.1.1.14
5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
|
–
|
|
|
BRENDA:
BS289580
|
|
|
|
L-histidine + 4-methylsulfanyl-2-oxobutanoate <=> 3-(1H-imidazol-4-yl)-2-oxopropanoate + L-methionine
|
2.6.1.117
L-glutamine---4-(methylsulfanyl)-2-oxobutanoate aminotransferase
2.6.1.57
aromatic-amino-acid transaminase
|
–
–
|
|
|
BRENDA:
BS353577
|
|
|
|
benzyloxycarbonyl-Phe-Met + H2O <=> benzyloxycarbonyl-Phe + L-methionine
|
3.4.17.4
Gly-Xaa carboxypeptidase
|
–
|
|
|
BRENDA:
BS73996
|
|
|
|
Met-Ala-Ser + H2O <=> L-methionine + Ala-Ser
|
3.4.11.15
aminopeptidase Y
3.4.11.18
methionyl aminopeptidase
3.4.11.4
tripeptide aminopeptidase
3.4.11.9
Xaa-Pro aminopeptidase
|
–
–
–
–
|
|
|
BRENDA:
BS361399
|
|
|
|
L-methionine_(R)-S-oxide + dithioerythritol <=> L-methionine + dithioerythritol_disulfide + H2O
|
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS385025
|
|
|
|
L-Met-L-Met-L-Met + H2O <=> L-methionine + Met-Met
|
3.4.11.4
tripeptide aminopeptidase
3.4.14.1
dipeptidyl-peptidase I
3.4.14.2
dipeptidyl-peptidase II
|
–
–
–
|
|
|
BRENDA:
BS36277
|
|
|
|
N5-methyltetrahydropteroylheptaglutamate + L-homocysteine <=> tetrahydropteroylheptaglutamate + L-methionine
|
2.1.1.13
methionine synthase
|
–
|
|
|
BRENDA:
BS289524
|
|
|
|
N-acetyl-Ala-Met + H2O <=> N-acetyl-L-alanine + L-methionine
|
3.4.19.1
acylaminoacyl-peptidase
|
–
|
|
|
BRENDA:
BS365081
|
|
|
|
N-cyclohexanoyl-L-methionine + H2O <=> cyclohexanecarboxylate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS453327
|
|
|
|
Pro-Met + H2O <=> L-proline + L-methionine
|
3.4.13.18
cytosol nonspecific dipeptidase
|
–
|
|
|
BRENDA:
BS94928
|
|
|
|
L-Pro-L-Met + H2O <=> L-proline + L-methionine
|
3.4.13.9
Xaa-Pro dipeptidase
|
–
|
|
|
BRENDA:
BS385045
|
|
|
|
Met-Val + H2O <=> L-methionine + L-valine
|
3.4.11.18
methionyl aminopeptidase
3.4.13.12
Met-Xaa dipeptidase
|
–
–
|
|
|
BRENDA:
BS361432
|
|
|
|
Met-Thr + H2O <=> L-methionine + L-threonine
|
3.4.11.18
methionyl aminopeptidase
3.4.13.12
Met-Xaa dipeptidase
|
–
–
|
|
|
BRENDA:
BS64871
|
|
|
|
N-benzyloxycarbonyl-Ala-Met + H2O <=> Benzyloxycarbonyl-Ala + L-methionine
|
3.4.17.B4
3.4.17.B5
|
–
–
|
|
|
BRENDA:
BS421042
|
|
|
|
L-methionine + nicotinamide <=> L-homocysteine + N1-methylnicotinamide
|
2.1.1.1
nicotinamide N-methyltransferase
|
–
|
|
|
BRENDA:
BS370285
|
|
|
|
Met-Leu-Phe + H2O <=> L-methionine + Leu-Phe
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS412435
|
|
|
|
dimethylsulfonioacetate + DL-homocysteine <=> methylthioacetate + L-methionine
|
2.1.1.3
thetin---homocysteine S-methyltransferase
|
–
|
|
|
BRENDA:
BS451817
|
|
|
|
Met-Pro-Gly + H2O <=> L-methionine + Pro-Gly
|
3.4.11.9
Xaa-Pro aminopeptidase
|
–
|
|
|
BRENDA:
BS385015
|
|
|
|
L-methionine_(R)-S-oxide + thionein <=> L-methionine + thionein_disulfide + H2O
|
1.8.4.B3
|
–
|
|
|
BRENDA:
BS397633
|
|
|
|
Met-Lys-bradykinin + H2O <=> L-methionine + kallidin
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361416
|
|
|
|
L-methionine_(R)-S-oxide + dithiothreitol <=> L-methionine + dithiothreitol_disulfide
|
1.8.4.12
peptide-methionine (R)-S-oxide reductase
1.8.4.B3
|
–
–
|
|
|
BRENDA:
BS377057
|
|
|
|
L-methionine_(S)-sulfoxide + 2 dithiothreitol <=> L-methionine + dithiothreitol_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS377058
|
|
|
|
Met-Ile + H2O <=> L-methionine + L-isoleucine
|
3.4.13.12
Met-Xaa dipeptidase
|
–
|
|
|
BRENDA:
BS64870
|
|
|
|
N-propionyl-L-methionine + H2O <=> propionate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS392810
|
|
|
|
N-2,2-dimethylpropionyl-L-methionine + H2O <=> propionate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS392699
|
|
|
|
N-benzoyl-L-methionine + H2O <=> benzoate + L-methionine
|
3.4.17.B1
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
3.5.1.32
hippurate hydrolase
|
–
–
–
|
|
|
BRENDA:
BS385267
|
|
|
|
Tyr-Tyr-Thr-Ser-Pro-Met-Cys-Ala-Pro-Ala-Arg-Ser-Met-Leu-Leu-Thr-Gly-Asn + S-adenosyl-L-methionine <=> Tyr-Tyr-Thr-Ser-Pro-Met-3-oxo-L-Ala-Ala-Pro-Ala-Arg-Ser-Met-Leu-Leu-Thr-Gly-Asn + L-methionine + 5''-deoxyadenosine + SO2 + Sulfide
|
1.8.98.7
cysteine-type anaerobic sulfatase-maturating enzyme
|
–
|
|
|
BRENDA:
BS439956
|
|
|
|
Ac-AVPSCIPSRASILTGM-NH2 + S-adenosyl-L-methionine + Dithionite <=> Ac-AVPS-3-oxo-L-Ala-IPSRASILTGM-NH2 + L-methionine + 5''-deoxyadenosine + SO2 + Sulfide
|
1.8.98.7
cysteine-type anaerobic sulfatase-maturating enzyme
|
–
|
|
|
BRENDA:
BS438989
|
|
|
|
Ac-FENAYTAVPSCIASRASILTMSQ-NH2 + S-adenosyl-L-methionine + Dithionite <=> Ac-FENAYTAVPS-3-oxo-L-Ala-IASRASILTMSQ-NH2 + L-methionine + 5''-deoxyadenosine + SO2 + Sulfide
|
1.8.98.7
cysteine-type anaerobic sulfatase-maturating enzyme
|
–
|
|
|
BRENDA:
BS438992
|
|
|
|
Ac-YTAVPSCIPSRASILTGM + S-adenosyl-L-methionine + Dithionite <=> Ac-YTAVPS-3-oxo-L-Ala-IPSRASILTGM + L-methionine + 5''-deoxyadenosine + SO2 + Sulfide
|
1.8.98.7
cysteine-type anaerobic sulfatase-maturating enzyme
|
–
|
|
|
BRENDA:
BS438996
|
|
|
|
Ac-YYTSPMCAPARSMLLTGN + S-adenosyl-L-methionine <=> Ac-YYTSPM-3-oxo-L-Ala-APARSMLLTGN + L-methionine + 5''-deoxyadenosine + SO2 + Sulfide
|
1.8.98.7
cysteine-type anaerobic sulfatase-maturating enzyme
|
–
|
|
|
BRENDA:
BS438997
|
|
|
|
L-methionine_(R)-S-oxide + glutathione <=> L-methionine + GSSG + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS426576
|
|
|
|
N-isopentanoyl-L-methionine + H2O <=> Isovalerate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS453330
|
|
|
|
Met-Ala-Met + H2O <=> L-methionine + Ala-Met
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361418
|
|
|
|
L-Met-D-Glu + H2O <=> L-methionine + D-glutamate
|
3.4.13.19
membrane dipeptidase
|
–
|
|
|
BRENDA:
BS412294
|
|
|
|
Met-Ser-Gly + H2O <=> L-methionine + L-Ser-Gly
|
3.4.11.9
Xaa-Pro aminopeptidase
|
–
|
|
|
BRENDA:
BS385017
|
|
|
|
S-(4-Bromophenyl)-L-cysteine + 4-methylsulfanyl-2-oxobutanoate <=> S-(4-Bromophenyl)-3-thiopyruvate + L-methionine
|
2.6.1.75
cysteine-conjugate transaminase
|
–
|
|
|
BRENDA:
BS356901
|
|
|
|
S-adenosyl-L-methionine + reduced_methyl_viologen + formate_acetyltransferase-glycine <=> 5''-deoxyadenosine + L-methionine + methyl_viologen + formate_acetyltransferase-glycine-2-yl-radical
|
1.97.1.4
[formate-C-acetyltransferase]-activating enzyme
|
–
|
|
|
BRENDA:
BS380277
|
|
|
|
5-methyltetrahydropteroyl-gamma-glutamylglutamate + L-homocysteine <=> tetrahydrofolate-Glu + L-methionine
|
2.1.1.14
5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
|
–
|
|
|
BRENDA:
BS387620
|
|
|
|
Met-tRNA + H2O <=> L-methionine + tRNA
|
3.1.1.29
aminoacyl-tRNA hydrolase
|
–
|
|
|
BRENDA:
BS362957
|
|
|
|
S-adenosyl-L-methionine + I- <=> 5''-deoxy-5''-iodoadenosine + L-methionine
|
2.5.1.94
adenosyl-chloride synthase
|
–
|
|
|
BRENDA:
BS415293
|
|
|
|
L-kynurenine + 4-methylsulfanyl-2-oxobutanoate <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-methionine
|
2.6.1.63
kynurenine---glyoxylate transaminase
|
–
|
|
|
BRENDA:
BS354010
|
|
|
|
L-2-aminobutanoate + 4-methylsulfanyl-2-oxobutanoate <=> 2-oxobutyrate + L-methionine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS379971
|
|
|
|
L-methionine + 2-oxobutyrate <=> 4-methylsulfanyl-2-oxobutanoate + 2-aminobutanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
–
|
|
|
BRENDA:
BS356571
|
|
|
|
4-methylsulfanyl-2-oxobutanoate + L-tyrosine <=> L-methionine + 4-hydroxyphenylpyruvate
|
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.88
methionine transaminase
|
–
–
|
|
|
BRENDA:
BS353570
|
|
|
|
N5-methyltetrahydropteroylpentaglutamate + L-homocysteine <=> Tetrahydropteroylpentaglutamate + L-methionine
|
2.1.1.13
methionine synthase
|
–
|
|
|
BRENDA:
BS289523
|
|
|
|
N-butanoyl-L-methionine + H2O <=> Butyrate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS392781
|
|
|
|
L-methionine_(R)-S-oxide + dithiothreitol <=> L-methionine + thioredoxin_disulfide + H2O
|
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS385027
|
|
|
|
L-methionine_2-naphthylamide + H2O <=> L-methionine + 2-Naphthylamine
|
3.3.2.6
leukotriene-A4 hydrolase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.14
cytosol alanyl aminopeptidase
3.4.11.18
methionyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
3.4.11.6
aminopeptidase B
3.4.22.16
cathepsin H
3.5.1.13
aryl-acylamidase
|
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS140296
|
|
|
|
N-palmitoyl-L-Met + H2O <=> palmitate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS414989
|
|
|
|
Ac-YYTSPMSeCAPARSMLLTGN + S-adenosyl-L-methionine <=> Ac-YYTSPM-3-oxo-L-Ala-APARSMLLTGN + L-methionine + 5''-deoxyadenosine + SO2 + selenium
|
1.8.98.7
cysteine-type anaerobic sulfatase-maturating enzyme
|
–
|
|
|
BRENDA:
BS439000
|
|
|
|
Met-Pro-Ala + H2O <=> L-methionine + Pro-Ala
|
3.4.11.26
intermediate cleaving peptidase 55
3.4.11.9
Xaa-Pro aminopeptidase
3.4.13.9
Xaa-Pro dipeptidase
|
–
–
–
|
|
|
BRENDA:
BS450276
|
|
|
|
5-L-Glutamyl-L-methionine + Gly-Gly <=> L-methionine + 5-L-glutamyl-Gly-Gly
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS375996
|
|
|
|
L-methionine_(R)-S-oxide + reduced_benzyl_viologen <=> L-methionine + Oxidized_benzyl_viologen + H2O
|
1.8.5.B1
|
–
|
|
|
BRENDA:
BS441524
|
|
|
|
L-methionine_(S)-sulfoxide + reduced_benzyl_viologen <=> L-methionine + Oxidized_benzyl_viologen + H2O
|
1.8.5.B1
|
–
|
|
|
BRENDA:
BS441525
|
|
|
|
L-methionine + H2O + 2 cytochrome_b <=> 4-methylsulfanyl-2-oxobutanoate + NH3 + 2 reduced_cytochrome_b
|
1.4.99.B3
|
–
|
|
|
BRENDA:
BS439677
|
|
|
|
methionine_sulfoxide + electron_donor <=> L-methionine + oxidized_electron_donor + H2O
|
1.7.2.3
trimethylamine-N-oxide reductase
|
–
|
|
|
BRENDA:
BS259489
|
|
|
|
methionine_sulfoxide + reduced_2,6-dichlorophenolindophenol <=> L-methionine + H2O + oxidized_dichlorophenolindophenol
|
1.8.5.3
respiratory dimethylsulfoxide reductase
|
–
|
|
|
BRENDA:
BS414850
|
|
|
|
3-(2-furyl)acryloyl-L-methionine + H2O <=> 2-furylacrylic_acid + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS414012
|
|
|
|
L-Met-7-amido-4-carbamoylmethylcoumarin + H2O <=> L-methionine + 7-amino-4-carbamoylmethylcoumarin
|
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
|
–
–
|
|
|
BRENDA:
BS432041
|
|
|
|
L-methionine_(R)-S-oxide + dithiothreitol <=> L-methionine + DTT_disulfide + H2O
|
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS385026
|
|
|
|
L-methionine_(S)-sulfoxide + dithiothreitol <=> L-methionine + DTT_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS385028
|
|
|
|
Met-enkephalin + H2O <=> L-methionine + Enkephalin
|
3.4.11.2
membrane alanyl aminopeptidase
|
–
|
|
|
BRENDA:
BS380655
|
|
|
|
Met-Met-Ala + H2O <=> L-methionine + Met-Ala
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS412436
|
|
|
|
L-leucine + 3-methylthio-2-oxobutanoate <=> 4-methyl-2-oxopentanoate + L-methionine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356512
|
|
|
|
Met-Ala-Pro-interleukin_2 + H2O <=> L-methionine + Ala-Pro-interleukin_2
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361414
|
|
|
|
Met-Ile-Phe-ricin_A + H2O <=> L-methionine + Ile-Phe-ricin_A
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361415
|
|
|
|
L-methionine_(S)-sulfoxide + dithiothreitol <=> L-methionine + oxidized_DTT + H2O
|
1.8.4.13
L-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS385021
|
|
|
|
Met-Arg-Phe + H2O <=> L-methionine + Arg-Phe
|
3.4.11.15
aminopeptidase Y
3.4.11.18
methionyl aminopeptidase
|
–
–
|
|
|
BRENDA:
BS361398
|
|
|
|
L-Met-L-Gln-L-Asp-onconase + H2O <=> L-methionine + L-Gln-L-Asp-onconase
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS385011
|
|
|
|
L-Met-N-myristoyltransferase + H2O <=> L-methionine + N-myristoyltransferase
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS385018
|
|
|
|
Met-Ala-His-Thr-Leu-Pro-Glu-Glu-Leu + H2O <=> L-methionine + Ala-His-Thr-Leu-Pro-Glu-Glu-Leu
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361425
|
|
|
|
Met-Ala-Pro-Thr-Ser-Ser-Ser-Thr-Lys-Lys-Thr-Gln-Leu + H2O <=> L-methionine + Ala-Pro-Thr-Ser-Ser-Ser-Thr-Lys-Lys-Thr-Gln-Leu
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361422
|
|
|
|
Met-Ala-Ser-(Gly)5-(Leu)3 + H2O <=> L-methionine + Ala-Ser-(Gly)5-(Leu)3
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361429
|
|
|
|
alpha2-antiplasmin + H2O <=> truncated_alpha2-antiplasmin + L-methionine
|
3.4.21.B28
|
–
|
|
|
BRENDA:
BS391267
|
|
|
|
Met-Pro-His-Thr-Leu-Pro-Glu-Glu + H2O <=> L-methionine + Pro-His-Thr-Leu-Pro-Glu-Glu
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361424
|
|
|
|
Met-Pro-Thr-Ser-Ser-Ser-Thr-Lys-Lys-Thr-Gln-Leu-Cys + H2O <=> L-methionine + Pro-Thr-Ser-Ser-Ser-Thr-Lys-Lys-Thr-Gln-Leu-Cys
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361421
|
|
|
|
L-methionine + S-CH2(CH3)2 <=> S-2-propylhomocysteine
|
4.4.1.11
methionine gamma-lyase
|
–
|
|
|
BRENDA:
BS19055
|
|
|
|
Met-Val-His-Thr-Leu-Pro-Glu-Glu-Leu + H2O <=> L-methionine + Val-His-Thr-Leu-Pro-Glu-Glu-Leu
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361423
|
|
|
|
L-methionine + 2-butylthiol <=> S-2-butylhomocysteine
|
4.4.1.11
methionine gamma-lyase
|
–
|
|
|
BRENDA:
BS19056
|
|
|
|
N-cyclopentanoyl-L-methionine + H2O <=> Cyclopentanoic_acid + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS453328
|
|
|
|
L-methionine_(S)-sulfoxide + tryparedoxin_I <=> L-methionine + tryparedoxin_I_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS414775
|
|
|
|
recombinant_human_methionine-interferon_alpha-2b + H2O <=> L-methionine + recombinant_human_interferon_alpha-2b
|
3.4.11.10
bacterial leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS419029
|
|
|
|
N-octanoyl-L-Met + H2O <=> Octanoate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS414983
|
|
|
|
N-myristoyl-L-Met + H2O <=> myristic_acid + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS414979
|
|
|
|
L-methionine_(S)-sulfoxide + glutaredoxin_2 <=> L-methionine + glutaredoxin_2_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS441526
|
|
|
|
Tyr-Tyr-Thr-Ser-Pro-Met-Ser-Ala-Pro-Ala-Arg-Ser-Met-Leu-Leu-Thr-Gly-Asn + S-adenosyl-L-methionine + Dithionite <=> Tyr-Tyr-Thr-Ser-Pro-Met-Ser-Ala-Pro-Ala-Arg-3-oxo-L-Ala-Met-Leu-Leu-Thr-Gly-Asn + L-methionine + 5''-deoxyadenosine + SO2 + H2O
|
1.1.98.7
serine-type anaerobic sulfatase-maturating enzyme
|
–
|
|
|
BRENDA:
BS439957
|
|
|
|
Ac-AVPSSIPSRASILTGM-NH2 + S-adenosyl-L-methionine + Dithionite <=> Ac-AVPS-3-oxo-L-Ala-IPSRASILTGM-NH2 + L-methionine + 5''-deoxyadenosine + SO2 + H2O
|
1.1.98.7
serine-type anaerobic sulfatase-maturating enzyme
|
–
|
|
|
BRENDA:
BS438990
|
|
|
|
Ac-YYTSPMTAPARSMLLTGN + S-adenosyl-L-methionine <=> Ac-YYTSPM-(2S)-2-amino-3-oxobutanoyl-APARSMLLTGN + L-methionine + 5''-deoxyadenosine + SO2 + H2O
|
1.1.98.7
serine-type anaerobic sulfatase-maturating enzyme
1.8.98.7
cysteine-type anaerobic sulfatase-maturating enzyme
|
–
–
|
|
|
BRENDA:
BS439001
|
|
|
|
S-adenosyl-L-methionine + reduced_flavodoxin + formate_acetyltransferase-glycine <=> 5''-deoxyadenosine + L-methionine + reduced_flavodoxin + formate_acetyltransferase-glycine + H+
|
1.97.1.4
[formate-C-acetyltransferase]-activating enzyme
|
–
|
|
|
BRENDA:
BR1412
|
|
|
|
N6-dimethylallyladenine37_in_tRNA + sulfur-(sulfur_carrier) + S-adenosyl-L-methionine <=> 2-thio-N6-dimethylallyladenine37_in_tRNA + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine
|
2.8.4.3
tRNA-2-methylthio-N6-dimethylallyladenosine synthase
|
–
|
|
|
BRENDA:
BS428822
|
|
|
|
GTP + S-adenosyl-L-methionine + reduced_electron_acceptor <=> (8S)-3'',8-cyclo-7,8-dihydroguanosine_5''-triphosphate + 5''-deoxyadenosine + L-methionine + oxidized_electron_acceptor
|
4.1.99.22
GTP 3',8-cyclase
|
–
|
|
|
BRENDA:
BR51777
|
|
|
|
alpha,beta-methylene-GTP + S-adenosyl-L-methionine + reduced_electron_acceptor <=> (8S)-3'',8-cyclo-7,8-dihydroguanosine-P[CH2]PP + 5''-deoxyadenosine + L-methionine + oxidized_electron_acceptor
|
4.1.99.22
GTP 3',8-cyclase
|
–
|
|
|
BRENDA:
BS437585
|
|
|
|
Glu-Ser-Val-(N6-octanoyl)Lys-Ala-Ala-Ser-Asp + sulfur-(sulfur_carrier) + S-adenosyl-L-methionine + reduced_[4Fe-4S]_dithionite <=> Glu-Ser-Val-(N6-lipoyl)Lys-Ala-Ala-Ser-Asp + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine + oxidized_[4Fe-4S]_dithionite
|
2.8.1.8
lipoyl synthase
|
–
|
|
|
BRENDA:
BS437575
|
|
|
|
Ac-FENAYTAVPSSIASRASILTGMS-NH2 + S-adenosyl-L-methionine <=> Ac-FENAYTAVPS-3-oxo-L-Ala-IASRASILTGMS-NH2 + L-methionine + 5''-deoxyadenosine
|
1.1.98.7
serine-type anaerobic sulfatase-maturating enzyme
|
–
|
|
|
BRENDA:
BS438993
|
|
|
|
Ac-YYTSPMSAPARSMLLTGN + S-adenosyl-L-methionine <=> Ac-YYTSPM-3-oxo-L-Ala-APARSMLLTGN + L-methionine + 5''-deoxyadenosine
|
1.1.98.7
serine-type anaerobic sulfatase-maturating enzyme
1.8.98.7
cysteine-type anaerobic sulfatase-maturating enzyme
|
–
–
|
|
|
BRENDA:
BS438998
|
|
|
|
alpha-D-ribose_1-methylphosphonate_5-phosphate + S-adenosyl-L-methionine + reduced_electron_acceptor <=> 5-phospho-alpha-D-ribose_1,2-cyclic_phosphate + methane + L-methionine + 5''-deoxyadenosine + oxidized_electron_acceptor
|
4.7.1.1
alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase
|
–
|
|
|
BRENDA:
BR50481
|
|
|
|
(5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine_(in_double-helical_DNA) + S-adenosyl-L-methionine + 2 H+ <=> thymidylyl-(3''-5'')-thymidylate_(in_DNA) + 5''-deoxyadenosine + L-methionine
|
4.1.99.14
spore photoproduct lyase
|
–
|
|
|
BRENDA:
BS417823
|
|
|
|
S-adenosyl-L-methionine + methyl-cob(III)alamin + 2-hydroxyethylphosphonate <=> 5''-deoxyadenosine + L-methionine + cob(III)alamin + (S)-2-hydroxypropylphosphonate
|
2.1.1.308
cytidylyl-2-hydroxyethylphosphonate methyltransferase
|
–
|
|
|
BRENDA:
BS429389
|
|
|
|
protein_N6-(octanoyl)lysine + sulfur-(sulfur_carrier) + S-adenosyl-L-methionine + reduced_[4Fe-4S]_cluster <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine + oxidized_[4Fe-4S]_cluster
|
2.8.1.8
lipoyl synthase
|
–
|
|
|
BRENDA:
BS436549
|
|
|
|
protein_N6-(octanoyl)lysine + sulfur + S-adenosyl-L-methionine <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + 2 L-methionine + 2 5''-deoxyadenosyl_radicals
|
2.8.1.8
lipoyl synthase
|
–
|
B
|
|
BRENDA:
BS380225
|
|
|
|
S-adenosyl-L-methionine + 5-Deazariboflavin + formate_acetyltransferase-glycine <=> 5''-deoxyadenosine + L-methionine + 5-deazariboflavin_semiquinone + formate_acetyltransferase-glycine
|
1.97.1.4
[formate-C-acetyltransferase]-activating enzyme
|
–
|
|
|
BRENDA:
BS443891
|
|
|
|
(5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine + S-adenosyl-L-methionine <=> thymidylyl-(3''->5'')-thymidylate + 5''-deoxyadenosine + L-methionine
|
4.1.99.14
spore photoproduct lyase
|
–
|
|
|
BRENDA:
BS415903
|
|
|
|
(5''R)-alpha-5''(6''H)-bithymine + S-adenosyl-L-methionine <=> thymidylyl-(3''-5'')-thymidylate + 5''-deoxyadenosine + L-methionine
|
4.1.99.14
spore photoproduct lyase
|
–
|
|
|
BRENDA:
BS391028
|
|
|
|
N6-dimethylallyladenine37_in_tRNA + sulfur-(sulfur_carrier) + S-adenosyl-L-methionine + reduced_electron_acceptor <=> 2-sulfanyl-N6-dimethylallyladenine37_in_tRNA + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine + electron_acceptor
|
2.8.4.3
tRNA-2-methylthio-N6-dimethylallyladenosine synthase
|
–
|
|
|
BRENDA:
BR50976
|
|
|
|
N6-L-threonylcarbamoyladenine37_in_tRNA + sulfur-(sulfur_carrier) + S-adenosyl-L-methionine + reduced_electron_acceptor <=> 2-sulfanyl-N6-L-threonylcarbamoyladenine37_in_tRNA + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine + electron_acceptor
|
2.8.4.5
tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase
|
–
|
|
|
BRENDA:
BR50982
|
|
|
|
S-adenosyl-L-methionine + reduced_flavodoxin + formate_acetyltransferase-glycine <=> 5''-deoxyadenosine + L-methionine + flavodoxin + formate_acetyltransferase-glycine-2-yl-radical
|
1.97.1.4
[formate-C-acetyltransferase]-activating enzyme
|
–
|
|
|
BRENDA:
BS6766
|
|
|
|
S-adenosyl-L-methionine + reduced_flavodoxin + [pyruvate_formate-lyase]-glycine <=> L-methionine + 5''-deoxyadenosine + [pyruvate_formate-lyase]-glycine_radical + flavodoxin
|
1.97.1.4
[formate-C-acetyltransferase]-activating enzyme
|
–
|
|
|
BRENDA:
BS451802
|
|
|
|
L-aspartate89-[ribosomal_protein_S12]-methanethiol + S-adenosyl-L-methionine + reduced_acceptor <=> 3-(methylsulfanyl)-L-aspartate89-[ribosomal_protein_S12] + L-methionine + 5''-deoxyadenosine + oxidized_acceptor
|
2.8.4.4
[ribosomal protein S12] (aspartate89-C3)-methylthiotransferase
|
–
|
|
|
BRENDA:
BR50980
|
|
|
|
biotin-PEG-Glu-Ser-Val-([8,8,8-2H3]-N6-octanoyl)Lys-Ala-Ala-Ser-As + sulfur-(sulfur_carrier) + S-adenosyl-L-methionine + reduced_[4Fe-4S]-ferredoxin <=> biotin-PEG-Glu-Ser-Val-([8,8,8-2H3]-N6-lipoyl)Lys-Ala-Ala-Ser-As + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine + oxidized_[4Fe-4S]_ferredoxin
|
2.8.1.8
lipoyl synthase
|
–
|
|
|
BRENDA:
BS437226
|
|
|
|
H_protein_N6-(octanoyl)lysine + sulfur-(sulfur_carrier) + S-adenosyl-L-methionine + reduced_[2Fe-2S]_dithionite <=> H_protein_N6-(lipoyl)lysine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine + oxidized_[2Fe-2S]_dithionite
|
2.8.1.8
lipoyl synthase
|
–
|
|
|
BRENDA:
BS437598
|
|
|
|
H_protein_N6-(octanoyl)lysine + sulfur-(sulfur_carrier) + S-adenosyl-L-methionine + reduced_[2Fe-2S]_flavodoxin <=> H_protein_N6-(lipoyl)lysine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine + oxidized_[2Fe-2S]_flavodoxin
|
2.8.1.8
lipoyl synthase
|
–
|
|
|
BRENDA:
BS437599
|
|
|
|
[8,8,8-2H3]-octanoyl-H_protein + sulfur-(sulfur_carrier) + S-adenosyl-L-methionine + reduced_[4Fe-4S]_dithionite <=> [8,8,8-2H3]-lipoyl-H_protein + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine + oxidized_[4Fe-4S]_dithionite
|
2.8.1.8
lipoyl synthase
|
–
|
|
|
BRENDA:
BS437990
|
|
|
|
a_PqqA_peptide + S-adenosyl-L-methionine <=> a_PqqA_peptide_with_linked_Glu-Tyr_residues + 5''-deoxyadenosine + L-methionine
|
1.21.98.4
PqqA peptide cyclase
|
–
|
|
|
BRENDA:
BR52480
|
|
|
|
dethiobiotin + sulfur + S-adenosyl-L-methionine <=> 9-Mercaptodethiobiotin + L-methionine + 5''-deoxyadenosine
|
2.8.1.6
biotin synthase
|
–
|
|
|
BRENDA:
BS426289
|
|
|
|
2-hydroxyethylphosphonate + S-adenosyl-L-methionine + methylcobalamin <=> (S)-2-hydroxypropylphosphonate + L-methionine + 5''-deoxyadenosine + Cobalamin
|
2.1.1.308
cytidylyl-2-hydroxyethylphosphonate methyltransferase
|
–
|
|
|
BRENDA:
BS406977
|
|
|
|
S-adenosyl-L-methionine + a_[Klebsiella_pneumoniae_sulfatase]-L-serine <=> [Klebsiella_pneumoniae_sulfatase]-3-oxo-L-alanine + 5''-deoxyadenosine + L-methionine
|
1.1.98.7
serine-type anaerobic sulfatase-maturating enzyme
|
–
|
|
|
BRENDA:
BS454500
|
|
|
|
S-adenosyl-L-methionine + [Klebsiella_pneumoniae_sulfatase]-L-serine <=> [Klebsiella_pneumoniae_sulfatase]-3-oxo-L-alanine + 5''-deoxyadenosine + L-methionine
|
1.1.98.7
serine-type anaerobic sulfatase-maturating enzyme
|
–
|
|
|
BRENDA:
BS456646
|
|
|
|
S-adenosyl-L-methionine + [periplasmic_sulfatase_AtsA]-L-serine <=> [periplasmic_sulfatase_AtsA]-3-oxo-L-alanine + 5''-deoxyadenosine + L-methionine
|
1.1.98.7
serine-type anaerobic sulfatase-maturating enzyme
|
–
|
|
|
BRENDA:
BS454638
|
|
|
|
protein_N6-(octanoyl)lysine + sulfur-(sulfur_carrier) + S-adenosyl-L-methionine + [2Fe-2S]-center <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine + [2Fe-2S]-center
|
2.8.1.8
lipoyl synthase
|
–
|
|
|
BRENDA:
BS436548
|
|
|
|
MAPLDLDRWGRPVGRRRRPVRVYP-OH + H2O <=> L-methionine + APLDLDRWGRPVGRRRRPVRVYP-OH
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS450261
|
|
|
|
N-2,2-dimethylpropionyl-L-methionine + H2O <=> N-2,2-dimethyl-propionate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS453326
|
|
|
|
5-methyltetrahydropteroyl-gamma-glutamyl-gamma-glutamyl-gamma-glutamylglutamate + L-homocysteine <=> tetrahydropteroyl-gamma-glutamyl-gamma-glutamyl-gamma-glutamylglutamate + L-methionine
|
2.1.1.14
5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
|
–
|
|
|
BRENDA:
BS451810
|
|
|
|
S-methyl-L-methionine + L-homocysteine <=> L-methionine + Se-methyl-L-homocysteine
|
2.1.1.280
selenocysteine Se-methyltransferase
|
–
|
|
|
BRENDA:
BS454643
|
|
|
|
Met-Ala-Ser-His-Arg-Trp-Asp-Trp + H2O <=> L-methionine + Ala-Ser-His-Arg-Trp-Asp-Trp
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361441
|
|
|
|
Met-Ala-Ser-Lys-(biotin)-Gly + H2O <=> L-methionine + Ala-Ser-Lys-(biotin)-Gly
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361448
|
|
|
|
Met-Ala-Ser-Trp + H2O <=> L-methionine + Ala-Ser-Trp
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361446
|
|
|
|
Met-Gly-Ala-Gln-Phe-Ser-Lys-Thr + H2O <=> L-methionine + Gly-Ala-Gln-Phe-Ser-Lys-Thr
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361447
|
|
|
|
Met-Gly-Ser-His-Arg-Trp-Asp-Trp + H2O <=> L-methionine + Gly-Ser-His-Arg-Trp-Asp-Trp
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361440
|
|
|
|
Met-Pro-Ser-His-Arg-Trp-Asp-Trp + H2O <=> L-methionine + Pro-Ser-His-Arg-Trp-Asp-Trp
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361444
|
|
|
|
L-Met-L-Ser-L-Ser-L-His-L-Arg-L-Trp-L-Asp-L-Trp + H2O <=> L-methionine + Ser-Ser-His-Arg-Trp-Asp-Trp
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS405629
|
|
|
|
Met-Ser-Ser-His-Arg-Trp-Asp-Trp + H2O <=> L-methionine + Ser-Ser-His-Arg-Trp-Asp-Trp
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361442
|
|
|
|
Met-Thr-Ser-His-Arg-Trp-Asp-Trp + H2O <=> L-methionine + Thr-Ser-His-Arg-Trp-Asp-Trp
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361443
|
|
|
|
Met-Val-Ser-His-Arg-Trp-Asp-Trp + H2O <=> L-methionine + Val-Ser-His-Arg-Trp-Asp-Trp
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS361445
|
|
|
|
5-L-Glutamyl-L-methionine <=> 5-oxoproline + L-methionine
|
4.3.2.9
gamma-glutamylcyclotransferase
|
–
|
|
|
BRENDA:
BS321705
|
|
|
|
L-pyroglutamyl-Met + H2O <=> 5-oxoproline + L-methionine
|
3.4.19.3
pyroglutamyl-peptidase I
|
–
|
|
|
BRENDA:
BS74126
|
|
|
|
N-hexanoyl-L-methionine + H2O <=> hexanoate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS392795
|
|
|
|
N-cyclohexanoyl-L-methionine + H2O <=> hexanoate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS392789
|
|
|
|
3-(2-furyl)acryloyl-L-Phe-L-Met + H2O <=> 3-(2-furyl)acryloyl-L-Phe + L-methionine
|
3.4.17.1
carboxypeptidase A
|
–
|
|
|
BRENDA:
BS407973
|
|
|
|
L-lysine + 4-methylsulfanyl-2-oxobutanoate <=> 6-Amino-2-oxohexanoate + L-methionine
|
2.6.1.57
aromatic-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353578
|
|
|
|
Benzyloxycarbonyl-Pro-Met + H2O <=> Benzyloxycarbonyl-Pro + L-methionine
|
3.4.17.16
membrane Pro-Xaa carboxypeptidase
|
–
|
|
|
BRENDA:
BS15034
|
|
|
|
L-cysteine + 4-methylsulfanyl-2-oxobutanoate <=> 3-Mercaptopyruvate + L-methionine
|
2.6.1.57
aromatic-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353580
|
|
|
|
L-isoleucine + 4-methylsulfanyl-2-oxobutanoate <=> 3-methyl-2-oxopentanoate + L-methionine
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.57
aromatic-amino-acid transaminase
|
–
–
|
|
|
BRENDA:
BS353576
|
|
|
|
2''-deoxyadenosyl-L-methionine + F- <=> 2''-deoxy-5''-fluoroadenosine + L-methionine
|
2.5.1.63
adenosyl-fluoride synthase
|
–
|
|
|
BRENDA:
BS387066
|
|
|
|
Met-Ala-Ala + H2O <=> L-methionine + Ala-Ala
|
3.4.11.18
methionyl aminopeptidase
3.4.11.9
Xaa-Pro aminopeptidase
3.4.13.9
Xaa-Pro dipeptidase
|
–
–
–
|
|
|
BRENDA:
BS412431
|
|
|
|
L-Met-PSI[C(O)S]Gly-L-Phe + H2O <=> [2-mercapto-ethanoyl]-Phe + L-methionine
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS392587
|
|
|
|
Met-Ala-Met-Lys-Ser + H2O <=> L-methionine + Ala-Met-Lys-Ser
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS392582
|
|
|
|
Met-Ser + H2O <=> L-methionine + L-serine
|
3.4.11.18
methionyl aminopeptidase
3.4.13.12
Met-Xaa dipeptidase
|
–
–
|
|
|
BRENDA:
BS64869
|
|
|
|
beta-Asp-Met + H2O <=> L-aspartate + L-methionine
|
3.4.19.5
beta-aspartyl-peptidase
|
–
|
|
|
BRENDA:
BS361792
|
|
|
|
Met-paranitroanilide + H2O <=> L-methionine + 4-nitroaniline
|
3.4.22.40
bleomycin hydrolase
|
–
|
|
|
BRENDA:
BS37010
|
|
|
|
betaine + DL-homocysteine <=> N,N-dimethylglycine + L-methionine
|
2.1.1.5
betaine---homocysteine S-methyltransferase
|
–
|
|
|
BRENDA:
BS451874
|
|
|
|
Ala-Met + H2O <=> L-alanine + L-methionine
|
3.4.13.12
Met-Xaa dipeptidase
3.4.13.19
membrane dipeptidase
|
–
–
|
|
|
BRENDA:
BS64877
|
|
|
|
N-chloroacetyl-L-methionine + H2O <=> Chloroacetate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS189732
|
|
|
|
2-aminobenzoyl-Phe-Arg-Met + H2O <=> 2-aminobenzoyl-Phe-Arg + L-methionine
|
3.4.18.1
cathepsin X
|
–
|
|
|
BRENDA:
BS380943
|
|
|
|
L-methionine <=> methanethiol + L-2-aminobutanoate
|
4.4.1.13
cysteine-S-conjugate beta-lyase
|
–
|
|
|
BRENDA:
BS389048
|
|
|
|
L-Vinylglycine + methanethiol <=> L-methionine
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353532
|
|
|
|
Met-Met + H2O <=> L-methionine + L-methionine
|
3.4.11.13
clostridial aminopeptidase
3.4.13.12
Met-Xaa dipeptidase
3.4.13.19
membrane dipeptidase
|
–
–
–
|
|
|
BRENDA:
BS64795
|
|
|
|
L-methionine + H2O <=> methanethiol + dimethyl_disulfide + dimethyl_trisulfide + 2-oxobutyrate
|
4.4.1.13
cysteine-S-conjugate beta-lyase
|
–
|
|
|
BRENDA:
BS412302
|
|
|
|
N-lauroyl-L-methionine + H2O <=> laurate + L-methionine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS385306
|
|
|
|
Met-Gly-Trp-Met-Asp + H2O <=> L-methionine + Gly-L-Trp-L-Met-L-Asp
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS405626
|
|
|
|
N-benzyloxycarbonyl-Gly-Pro-Met + H2O <=> Benzyloxycarbonyl-Gly-Pro + L-methionine
|
3.4.21.B28
|
–
|
|
|
BRENDA:
BS389233
|
|
|
|
N-acetyl-L-methionine + H2O <=> L-methionine + CO2
|
3.5.1.87
N-carbamoyl-L-amino-acid hydrolase
|
–
|
|
|
BRENDA:
BS389206
|
|
|
|
N-acetyl-L-methionine + H2O <=> L-methionine
|
3.5.1.17
acyl-lysine deacylase
|
–
|
|
|
BRENDA:
BS116215
|
|
|
|
Met-Pro + H2O <=> L-methionine + L-proline
|
3.4.11.18
methionyl aminopeptidase
3.4.11.9
Xaa-Pro aminopeptidase
3.4.13.9
Xaa-Pro dipeptidase
|
–
–
–
|
|
|
BRENDA:
BS36383
|
|
|
|
benzyloxycarbonyl-Gly-Met + H2O <=> Benzyloxycarbonyl-Gly + L-methionine
|
3.4.16.5
carboxypeptidase C
|
–
|
|
|
BRENDA:
BS391438
|
|
|
|
ATP + L-methionine + hydroxylamine <=> Methionine_hydroxamate + AMP + diphosphate
|
6.1.1.10
methionine---tRNA ligase
|
–
|
|
|
BRENDA:
BS42
|
|
|
|
ATP + L-methionine + tRNAMet <=> AMP + L-methionyl-tRNALys + diphosphate
|
6.1.1.6
lysine---tRNA ligase
|
–
|
|
|
BRENDA:
BS368909
|
|
|
|
ATP + L-methionine + tRNALeu <=> AMP + diphosphate + Met-tRNA
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS368897
|
|
|
|
L-aspartate + 4-methylsulfanyl-2-oxobutanoate <=> oxaloacetate + L-methionine
|
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.73
methionine---glyoxylate transaminase
|
–
–
|
|
|
BRENDA:
BS353581
|
|
|
|
L-Met-L-Pro-4-nitroanilide + H2O <=> L-methionine + Pro-p-nitroanilide
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS385013
|
|
|
|
5-L-glutamyl-4-nitroanilide + L-methionine <=> 4-nitroaniline + 5-L-Glutamyl-L-methionine
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS321632
|
|
|
|
L-Met-peptide + H2O <=> L-methionine + peptide
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS405631
|
|
|
|
Met-enkephalin-L-Tyr-Gly + H2O <=> L-methionine + enkephalin-L-Tyr-Gly
|
3.4.11.2
membrane alanyl aminopeptidase
|
–
|
|
|
BRENDA:
BS405817
|
|
|
|
L-leucine + L-methionine <=> Substance_P
|
3.1.1.7
acetylcholinesterase
|
–
|
|
|
BRENDA:
BS83085
|
|
|
|
L-glutamine + 4-methylsulfanyl-2-oxobutanoate <=> 2-oxoglutarate + L-methionine
|
2.6.1.73
methionine---glyoxylate transaminase
|
–
|
|
|
BRENDA:
BS353990
|
|
|
|
4-methylsulfanyl-2-oxobutanoate + L-glutamine <=> 2-oxoglutaramide + L-methionine
|
2.6.1.57
aromatic-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353573
|
|
|
|
L-alanine + 4-methylsulfanyl-2-oxobutanoate <=> pyruvate + L-methionine
|
2.6.1.15
glutamine---pyruvate transaminase
2.6.1.41
D-methionine---pyruvate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.44
alanine---glyoxylate transaminase
2.6.1.51
serine---pyruvate transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.73
methionine---glyoxylate transaminase
2.6.1.84
arginine---pyruvate transaminase
|
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS353579
|
|
|
|
Met-Ala-Pro-Thr + H2O <=> L-methionine + Ala-Pro-Thr
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS412432
|
|
|
|
Met-Asp-Gly + H2O <=> L-methionine + Asp-Gly
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS412433
|
|
|
|
Met-Phe-Gly + H2O <=> L-methionine + Phe-Gly
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS412437
|
|
|
|
Met-Pro-Gly-Gly + H2O <=> L-methionine + Pro-Gly-Gly
|
3.4.11.18
methionyl aminopeptidase
|
–
|
|
|
BRENDA:
BS412438
|
|
|
|
N-Succinyl-L-Met + H2O <=> succinate + L-methionine
|
not assigned
|
–
|
|
|
SABIO-RK:
9748
|
|
|
|
4-methylsulfanyl-2-oxobutanoate + L-isoleucine <=> L-methionine + (S)-3-methyl-2-oxopentanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
SABIO-RK:
12603
|
|